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When Modern Science Collides with Ayurveda

by NaturPro in Uncategorized Comments: 0

What do traditional Ayurveda and modern science have in common — other than repeated testing of hypotheses, and communication of evidence?  

Answer: They both warrant the usage of many herbs for health purposes based on rigorous observation in humans.  

While Ayurveda’s got nothing on our space age, it’s got its own chops as a well-developed, time-tested, evidence-based system. That’s partly why health claims based on traditional usage are recognized by some of the most highly regulated countries (thanks, Aussies and Canadians). But it’s no secret that the U.S. regulatory system completely ignores traditional usage, like in Ayurveda, when it comes to supporting evidence for product benefits. 

Turmeric Extract India

So it’s a good thing that more and more science is published proving Ayurvedic herbs work. And we’re talking the kind of science also used for proving drugs work — even though many herbs don’t work like drugs.  That’s right, many herbs in Ayurveda are increasingly corroborated by the gold standard for the evidence-based camp: their beloved randomized, placebo-controlled clinical trials. Turmeric and boswellia for inflammation. Ashwagandha for stress, stamina and sleep. Bacopa for cognitive support. It’s all there, accessible on PubMed and Google Scholar.

The facts are simple: Ayurveda is an early form of scientific medicine, because it’s actually founded on some central, scientific tenets. The main one being that the body’s composition can be balanced by its environment — including what we consume as food, drink and medicine. 

The evolution of plant medicines from prehistoric to today has always intrigued me. What did many generations of people before us know about health, that we should try to learn and preserve?  And — because the ancients aren’t ALWAYS right – what were their mistakes, or gaps that we need more scientific evidence on?  

There’s no shortage of similarities between the old and the new: Here’s a short list of my favorites between the traditional Ayurvedic and modern scientific application of many of our favorite herbs:

  1. Evidence-Based Practices. Ayurveda relies on empirical observations and historical practices of risk versus benefit. Modern science is similar, taking scientific evidence-based approaches and comparing them to currently accepted practices. Both systems recognize the importance of evaluating the effectiveness of treatments, and exploring new ideas. 
  • Holistic Approach to Health: Both Ayurveda and modern science acknowledge that health is a state of overall well-being, and not just the absence of disease. Prevention is worth a pound of cure, wherever you are in this world.
  • Use of Natural Products: Both traditional and modern scientific systems recognize the potential benefits of natural substances, including botanicals and other nutrients for promoting health and treating various health conditions. 
  • Digestive Health: Ayurveda places significant emphasis on digestive health, considering it the foundation of overall well-being. Modern research has explored the gastrointestinal benefits of traditionally fermented foods, spices and plant foods in Ayurveda. The validation of carminative and aromatic herbs like ginger and cinnamon by science are a couple examples. 
  • Adaptogens & Antioxidants: Ayurveda introduced the concept of adaptogens, botanicals that help the body adapt to stress and maintain balance. Modern research has investigated herbs like ashwagandha and holy basil as adaptogens. Also both Ayurveda and modern science acknowledge the importance of antioxidants in combating oxidative stress and preventing cellular damage. The ‘rasayana’ or rejuvenation tonics in Ayurveda are formulated with adaptogen- and antioxidant-rich herbs, and when investigated in clinical trials, have resulted in some promising findings. 
  • Mind-Body Connections: Ayurveda recognizes the interconnectedness of the mind and body. Similarly, modern science acknowledges the role of psychological and mental factors in physical and general health. For example, herbs like bacopa have been used in Ayurveda to support cognitive function, and modern research has studied its potential cognitive-enhancing effects.

For the full article, download the Natural Products Insider Digital Magazine.

The Bad Supplements List: Failed and Prohibited Products and Brands

by NaturPro in Uncategorized Comments: 0

The Bad Supplements List: Failed and Prohibited Products and Brands. The Bad Supplements List documents and reviews clear and reliable evidence, using publicly available information on testing and enforcement activities on U.S. dietary supplement brands and products.

What’s next.. vitamin gobstoppers?

by NaturPro in Uncategorized Comments: 0

Gummy Supplement Development

I remember the time I was called to an all-hands product development call regarding an amazing new technology. The crack team of young marketing whizzes had spent months compiling extensive market exploration research, mapping consumer needs, and diagramming product idea matrices. The culmination of this work was a groundbreaking product concept that was not only completely unique, but also met the unserved needs of millions of Americans. 

The beautiful, graphically pleasing Powerpoint deck was flush with consumer surveys and expert market analysis demonstrating persuasively why the next big supplement idea was… injectable botanicals. That’s right: plants stuck right through arms, into veins. The rationale?  B12 shots are a growth category. So why not a proprietary blend of herbs delivered with a 22-gauge needle for immediate action?

After I wiped up my spilled coffee, I took a deep breath and calmy explained the challenges with this well-presented concept. Injectables are always regulated as drugs, and supplements must always be swallowed (that’s by the mouth, and into the stomach, to be clear). Being solution-oriented, I listed a few alternatives that might fit the bill and would be, well… legal. 

There’s always a world of capsules and tablets with different sizes, shapes, compositions and release characteristics. And nothing beats a well-made capsule in terms of maximizing the benefit while minimizing unnecessary junk. And there’s a world of ingredients in different varieties and forms available to create a unique and groundbreaking capsule supplement.

But I do love powdered drink supplements. We can fit a lot of effective ingredients and dosages into a powdered drink format. They’re versatile and convenient. They are usually somewhat pleasant tasting. And for start-ups or test marketing, we can start with a low MOQ (minimum order quantity) for jars or pouches of powder, to test the market and bootstrap before committing to large order quantities. 

Of course, there’s everyone’s favorite candy-with-benefits: gummies. But gummies aren’t the only candy in the candy store — there’s more to the world of enjoyable supplement delivery forms than just squishy nuggets of sugar and cowhide extract. Supplements can also come in forms like chocolatey bites, sugar-free gel chews, and quick-dissolve tablets, to name a couple. 

Truth be told, we’ve only touched the surface of what is possible in supplement delivery forms (without touching injectables, of course).  Still waiting for the right opportunity are things like exploding vitamin candy, fizzy lifting energy drinks, and of course, the everlasting supplement gobstopper. (Not all of these have left the Wonka invention room – still a few kinks to be worked out.)

Botanical supplement formulation

But when we replace our marketing and innovation hats with our regulatory and quality assurance cap, we start to look at ‘supplement treats’ in a different way. The limited loading capacity, difficulty to ensure consistent dosage amount, and stability issues are the recurring headaches for manufacturing supplement treats. And safety: some of these formats taste so good that, like a great potato chip, it’s hard to eat just one. We should be careful that the dosage in our favorite candied supplements will not cause adverse events or provide more than the upper limit of nutrients if a Homer Simpson accidentally (or intentionally) eats ten or twenty of them in a sitting. So, be ready for potentially long and expensive development process to win the supplement “Nailed It” contest for some of these more palatable delivery forms.

Luckily, we don’t need to wait for a fanciful, candy-filled future. Some inspiration can be found in history, notably inside a 2,140 year old Roman shipwreck, the Relitto del Pozzino, discovered off the coast of Tuscany in the 1990s. The vessel contained the first known medicine, tins of soft tablets containing zinc, iron, starch, pine resin and beeswax. The Pozzino tablets serve as a reminder that swallowable or chewable supplement dosage forms don’t necessarily need to contain a lot of sugar or artificial ingredients. For example, there are more plant-based, organic excipients becoming available to replace ingredients of unspecified origin, like microcrystalline cellulose.

“Supplementified foods” has been a thing for a while, but we’ve only dipped our toes into the surface of the ocean. Within whole foods, we’ve seen calcium-fortified orange juice, algal DHA-supplemented milk, and probiotic-doped prunes. And in the world of packaged foods, a number of opportunities exist for supplementing or fortifying nutrients into drinks, snacks and dairy. 

Why do I consider these opportunities? Well, recall that much of the American population is at least marginally insufficient (if not deficient) in one or more nutrients, including calcium, Vitamin D, B-vitamins and iron. And more people are looking to food to get these nutrients. Teenagers and the elderly are two examples of vastly underserved populations in the nutrition world. Reaching sufficiency of these nutrients on a daily basis are critical for health and longevity, but a lot of people avoid taking pills until they need to. 

So there’s ample opportunity for supplement firms who deal with the more traditional formats to launch product forms that complement their existing product mix…

These exciting delivery forms and more insights are available in the exclusive Natural Products Insider Digital Magazine published in August 2023.

Smart Extracts for Smarter Supplements

by NaturPro in Uncategorized Comments: 0

The brain bone is connected to the hip bone — and just about everything else in our body. So when we think about antioxidant-rich botanicals that are good for our health, chances are they’re probably good for our brain too. Luckily, the past 20 years have given us an incredible amount of data to develop botanical-based supplements that are good for the noggin. 

In just the past year or two, dozens of well-designed clinical trials have been performed on brain botanicals. While some of these ingredients are ones you might expect, others, like pygmy smartweed and king’s salad, are a bit unusual. 

Pygmy smartweed (Persicaria minor)

Those of us trying to prevent cognitive decline as we age should be encouraged by research being done around the world.  Here’s a summary of just a few of these trials:

In a 2023 study with 323 older adults with mild cognitive impairment, an extract from lemon balm (Melissa officinalis) significantly improved clinical dementia scores versus placebo. this suggests that that lemon balm extract can help prevent cognitive decline.

A 2021 study found that sesame oil cake extract improved verbal memory and plasma beta amyloid in older adults with memory impairment. Sesame contains lignins and other antioxidants, such as sesamin, with an interesting bit of supporting evidence for anti-aging, vascular and brain health.

Spermidine is an endogenous polyamine which synchronizes many biological processes and is considered a potential longevity factor, like rapamycin. It’s found in cheese, mushrooms and whole grains, albeit in small amounts. A 2022 study found that a wheat germ extract containing 0.9 milligrams of spermidine per day did not modify memory or biomarkers. However, this dosage may be too small to impact cognition. Supplementing with higher doses of spermidine in clinical trials has potential to reverse memory deficit in people who are at risk of cognitive decline. 

Berries are also a big focus of cognitive research these days. While much research is mainly focusing on blueberries and other anthocyanin-rich berries, some traditional berries are showing up in clinical research. One recent study in 312 healthy people found an anthocyanin-rich Mulberry milk product (Memberry®) containing improved working memory and suppressed enzymes associated with brain function including acetylcholinesterase and monoamine oxidase (MAO).

Ulam raja, or king’s salad (Cosmos caudatus) is an antioxidant rich green vegetable traditionally consumed in Southeast Asia, including Malaysia, and Central America. A 2021 study found that 250 milligrams of Cosmos for 12 weeks improved mood disturbance and mental capacity in older adults with mild cognitive impairment. 

There’s also evidence to support another traditional Malay herb, a phenolic-rich plant called smartweed. In one study, 250 mg of pygmy smartweed(Persicaria minor) as Biokesum® improved visual memory, mood and brain derived neurotrophic factor (BDNF) after six months in older adults with mild cognitive impairment.

Outside of the research that helps us folks of a certain age, there’s been renewed interest in plant-derived ingredients that support a healthy mood state and sleep patterns for all ages — and without the downsides of stimulants or sedatives. One recent study looked at the effect of a multiherb extract (Euphytose®) containing hawthorn berry and ballota (Grecian horehound) for 14 days. This study in healthy people found reduced subjective anxiety versus placebo, along with lowered salivary amylase, a marker of stress that mimics cortisol.

A number of studies have focused on beneficial combinations of plant extracts for stress and mood. A 2022 study found that a combination of green tea and Rhodiola rosea combined with magnesium and B-vitamins found improved EEG theta state, and reduced stress and anxiety ratings in 100 healthy adults with moderate stress.

In another recent study, the combination of beetroot, ginseng and sage in a beverage in healthy adults was synergistically enhanced by apple and coffee berry extracts, for improvements in energy ratings and hemodynamic response.

While the attributes of corn have been extensively studied, research on other parts of the plant that are not typically eaten show promise. A standardized extract from corn leaf (as UP165) was evaluated for its impact on sleep quality in a small randomized controlled trial. Improvements in sleep quality, deep sleep time and improved mood state were observed versus placebo.

Bacopa monnieri has been studied for its improvement of higher order cognitive processes like memory and executive function. Recent studies suggest further potential on some of the more elusive emotional and sleep endpoints. A 2022 study in Australia found a Bacopa extract (CDRI 08®) improved cognitive flexibility and interpersonal problems in children with ADHD, compared to a placebo. This study adds to the oeuvre of well-designed research supporting Bacopa for the brain.

One of my favorite herbs to use for mental energy and alertness without the crash of caffeine is the spicy root known as galanga (Alpinia galanga), a cousin of ginger and turmeric. A study in healthy adults found improvements in both alertness and calmness with galanga extract (EnXtra®) compared to placebo. Notably, no increase of sleep disturbance was found, a benefit which may distinguish galanga from caffeine.

Lotus seeds are rich in phytonutrients, polyphenols, alkaloids and enzymes like superoxide dismutase – maybe partly why it’s been used as food and medicine for 7,000 years. Recent research suggests treatment with a standardized water extract of Lotus (Nelumbinis semen) seeds improved stress and depression ratings in people with mood issues.

Another 2022 study found that spirulina extract alleviated Alzheimer’s disease symptoms in people with dementia. This is the first study to show the cognitive impact of spirulina which is known more for its immune enhancing properties. This may partially explain the connection between brain health and immune health, as brain dysfunction is becoming increasingly linked to immune disorders.

Take echinacea for example. While echinacea is usually known for its immune enhancing properties, recent work suggests its impact on cognitive function as well. In a recent study, Echinacea angustifolia extract EP107™ at 40 or 80 milligrams led to improvement in emotional well-being in adults with mild to moderate anxiety.

While it’s not approved for supplements, a lot of promise is held for psilocybin, from Psilocybe cubensis. Among several studies, one studylooking at a single dose of 10 to 25 milligrams in 233 adults with treatment resistant depression was associated with lower severity of depression and anxiety, and an improved quality of life. Further research is needed to determine the best sources and doses and the right controls and setting for psilocybin research.

We don’t just have research on the botanicals we swallow. We have research on those we can inhale as well: a number of studies demonstrate the cognitive benefit of essential oil aromatherapy. Most recently, a 2022 study found that lavender or chamomile oil significantly improved ratings of stress, depression and anxiety within a month in older adults.

These days, supplementing with these herbs as part of the “king’s salad bar” may be our lotus of enlightenment on the natural path toward improved brain function and longevity. 

This article was originally published in the May 2023 Natural Products Insider Digital Edition.

Dietary Supplements Prohibited by Amazon.com

by NaturPro in Uncategorized Comments: 0

The following list of supplements are banned for sale by Amazon as of April 18, 2023. This list did not provide business owner names or contact information. Contact Amazon or FDA directly if you would like to learn more about these prohibited brands.

Visit the source page at the Amazon website for an updated list.

Amazon Prohibited Supplements

Known Prohibited Products

Amazon specifically prohibits the following Supplement products. These products are prohibited because they do not meet the checklist requirements. This list does not include all Supplement products prohibited by Amazon.

  • 1 Day Diet
  • 1 Minute Miracle products
  • 1,4 AD Bold
  • 1,4 AD Bold 200
  • 100% Healthy Food For Men
  • 17a PheraFLEX3-AD
  • 2 Day Diet
  • 2 Day Diet Slim Advance
  • 2 Own the Knight Silver 4000
  • 21 Double Slim
  • 24 Hours Diet
  • 24 Hours Diet
  • 24 Ince
  • 2x Powerful Slimming
  • 365 Skinny High Intensity
  • 3 Day Diet
  • 3 Days Fit
  • 3 Hard Knights
  • 3 KO
  • 3-AD
  • ‘3rd Degree’ by Xtreme Elite X
  • 3x Slimming Power
  • 3xGood Life & Perfect Shape
  • 4-AD
  • 4EVERON
  • 5x Imelda Perfect Slimming
  • 60-OXO Xtreme
  • 6-OXO
  • 69 MODE Blue 69
  • 7 Day Herbal Slim
  • 7 Days Diet
  • 7 Diet
  • 7 Diet Day/Night Formula
  • 72 Hours
  • 8 Factor Diet
  • 999 Fitness Essence
  • AB Slim manufactured by AB Care
  • ABC Dophilus Powder
  • Abdomen Smoothing Capsules
  • Absonutrix patches
  • Acacia Rigidula
  • Acai Berry Coffee
  • Acai Berry Soft Gel ABC
  • Acceleration
  • Accretropin
  • ACE Appetite Control Energy Dietary Supplement Pills
  • Achieving Zero
  • Achieving Zero Advanced
  • Achieving Zero evolve
  • Achieving Zero Max
  • AcraSX
  • Activ Otc
  • Activ Slim slimming capsules
  • Actra-Rx
  • Actra-Sx
  • Adam Free
  • Adam’s Secret
  • Adipotrim XT – fluoxetine
  • Adralin
  • Adrenal extract
  • Adrenalean
  • Adrenaline XR
  • A-Drol
  • AD-Rx
  • Advanced Slim 5
  • African Superman tablets
  • AFX
  • AH-89-XtremeArimaDex
  • Aisiyuan V26 Slimming Granules
  • Akttive Capsules
  • Akttive High Performance Fat Burner Gold capsules
  • Alfia Weight Loss Capsules
  • All products containing 30% or more synephrine
  • All products containing picamilon
  • All Vitamist Sprays
  • Allerclear
  • Alpha Male
  • Alpha Male Plus
  • Alpha T
  • Alteril Fast Acting Softgels
  • American Bangster
  • AmidrenApple Slim
  • Amour for him
  • AMP citrate (4-amino-2-methylpentane citrate)
  • AMPD Gold Bee Pollen
  • Anabolic Countdown 321zero
  • Anabolicum Vister
  • Anadraulic Pump
  • Anadrol
  • Anadroll
  • Anarchy Covalex
  • Anavar
  • Anavone
  • Andarine
  • Andriol Testocaps
  • Androstenedione
  • Androstenetrione
  • Anorex
  • AN-Rx
  • Ansomone
  • Antabolic
  • APEXXX
  • APL
  • Apple’s Quick Impact Weight Loss
  • ArimaDex
  • Arize Male Sexual Enhancer
  • ARO Black Series BURN
  • Arom-X
  • Arom-X UTT
  • Arom-XL
  • Arousin
  • Arth-Q
  • Artri Ajo King
  • Artri King
  • Asellacrin
  • Asia black
  • Asihuri Plus Forte
  • A-Slim 100%
  • Aspire Lite
  • Aspire One
  • Aspire36
  • Asset Bee Pollen
  • Asset Bold
  • Asset Extreme
  • Asset Extreme Plus
  • Australia Kangaroo Essence
  • Avaphinal
  • Avena Sativa
  • Averbol
  • AV-Rx
  • Aziffa
  • Bak Foong Pills
  • Bali Mojo
  • Baolong
  • Baschi
  • Basha Nut
  • Basha Nut 100% Fruit Soft Gel
  • Be Inspired
  • Beamonstar Extenze
  • Beamonstar Top Gun Enhancer
  • Beastdrol
  • Beta-nicotinamide mononucleotide (NMN, β-NMN)
  • Beautiful Slim Body
  • Bee Slim
  • Bee Thin
  • beFIT Total Garcinia Cambogia
  • Behavior Balance DMG Liquid
  • Bella Vi Amp’d Up
  • Bella Vi Insane Amp’d Up
  • Best Line Suplemento Alimenticio Capsules
  • Best Whips
  • Beyond Balance products
  • Bigger Longer
  • BioEmagrecim – fenproporex, furosemide, fluoxetine
  • BioEmagrecim, sample 1 – fenproporex
  • BioEmagrecim, sample 2 – fluoxetine, furosemide
  • Biogra
  • BioGuard
  • Biolean
  • Biorhythm SSIN Juice
  • Bio-Tropin
  • Black 3k 3000
  • Black Ant
  • Black Ant King
  • Black beauty
  • Black Cats
  • Black Gold X Advanced
  • Black ice
  • Black King Kong
  • Black knight
  • Black Label X
  • Black Mamba Hyperrush
  • Black Spider 25
  • Black Stallion 9000
  • Black Widow
  • Black widow
  • Black_3k
  • BlackStone Labs manufactured supplements
  • B-Lipo manufactured by Bethel Nutritional
  • Blood Rush Pump
  • Blue Diamond
  • Blue Fantasy capsules
  • Blue Panther Extreme 75k
  • Blue slim
  • Blue Steel
  • Blue Stinger
  • BMPEA
  • Bnew Beauty and Body
  • Bo Ying Compound manufactured by Eu Yan SangFlawless Beauty and Skin manufactured products
  • Body Bentonite Unique Healing Powder
  • Body Creator
  • Body Shaping
  • Body Shape Weight Loss System
  • Body Slimming
  • Boladrol
  • Boost Ultra
  • BOSC Enterprises Epi-Tren
  • Boss Number #Six
  • Botanical Slimming
  • Botanical Slimming (Red)
  • Botanical Slimming Soft Gel
  • Botanical Weight Loss
  • B-Perfect
  • Brahma Male Enhancement
  • BrainStrong products
  • Brazil Perfect
  • Brazil Potent Slimming Coffee
  • Brazilian Slimming Coffee
  • Breathe easy
  • Bromodrol
  • BSAID
  • BtRim Max
  • Bull’s Genital
  • BulletProof
  • Bumetanide
  • Burn 7
  • Burn Fat Now by Advance Herbal Research
  • Burn max
  • Burro en Primavera 60000
  • Casanova
  • Caution
  • CBD (cannabidiol)
  • Celerite Slimming Capsules
  • Celerite Slimming Tea
  • Cetilistat
  • CF-Rx
  • Chainsaw Extreme
  • Charge Extreme Energy Booster
  • Cheque Drops
  • China Brush
  • China white
  • China white
  • Chlorodehydromethyl testosterone
  • Cholestene
  • CholeSterin manufactured by Atrium
  • Chong Cao Zhang Bian Bao
  • Chorionic
  • Cialis
  • CigRX – anatabine
  • Cissus Drol
  • Citrus Fit Gold
  • Clalis
  • Clear Shot 3x Concentrate
  • Clenadrol-X
  • Clomed
  • Clomed-PCT
  • Clyamax
  • CoB9 Dietary Supplement
  • Cockstar
  • Code Red
  • Cold FX
  • Collagen Slim
  • Competitive Edge Labs X-tren
  • Component TH with Tylan 20 Doses
  • CONTROL
  • Core Zap
  • Corvalol products
  • Cougar Secret Honey VIP
  • Crane Beauty Green Algae Body Slimming Combination
  • Crane Beauty Green Algae Complex Tablets
  • Crane Beauty Green Algae Compound Tablets
  • Crane Beauty Green Algae Perfect Match
  • Creafuse Power (Grape & Fruit Punch)
  • Creatine Freak by PharmaFreak
  • CreOcell
  • Crescormon
  • CTD Labs manufactured supplements
  • Cyanostane
  • Cycle Support
  • D Stunner
  • Daidaihua Jiao Nang
  • Danabol
  • Dball or D-ball
  • DBOL
  • D-BOL
  • D-Drol
  • Deca Durabolin
  • Deca Nor 50
  • Deca-Bolin
  • Decavol
  • Deccabolin
  • Deep Relief Ibuprofen & Levomenthol Gel
  • Deer antler velter
  • Dekka150
  • Depth Charge
  • Dermatotropin
  • Desmthylsibutramine
  • Destroy the Enemy
  • Detonate by Gaspari Nutrition
  • Detox Intestinal Drawing Formula
  • Dexaprine
  • DEXAPRINE XR
  • Diablos ECA Fire Caps
  • Di-Acid Stim manufactured by Atrium
  • Dianabol
  • Dianadrol
  • Dick’s Hard Up
  • Didesmthylsibutramine
  • Dienedronel
  • Diet burn
  • Diet Master
  • Dinitrophenol or DNP
  • DMAA (1,3-dimethylamylamine)
  • DMBA (1,3-dimethylamylamine)
  • DMHA (1,5-dimethylhexylamine)
  • Doctor’s Best “Red Yeast Rice”
  • Dpol
  • D-pol
  • Dr. Reade Slim Sense
  • Dragon Power
  • Dream Body Slimming Capsule
  • Driven Sports manufactured supplements
  • Drotaverine
  • D-Stianozol
  • Du Zhong Jin Gu Wan
  • Dual Action Grow Tabs
  • Durabolin
  • Durazest For Men
  • Duro Extend
  • Duro Extend Capsules for Men
  • Dyma-Burn
  • Dyma-Burn Xtreme
  • Dymetadrine Xtreme
  • Dymethazine
  • Dymethazine
  • Dymethazine/Reversitol Combo Pack
  • Dynamizm
  • Dynapep Energy Microshot
  • E.T Tren-250
  • ECA Fatburner
  • EDGE Amplified Weight Release
  • Eight Factor Diet
  • Ejaculoid XXTREME
  • El Torito Black Bull Power 500 mg
  • El Torito Extreme 500 mg
  • El Torito Plus 1000 mg
  • Elimite
  • Elimulating Weight & Toxin Keeping Beauty products
  • Emperor’s Tea Pill (Tian Huang Bu Xin Wan)
  • Endotropin
  • Endowmax
  • Energel
  • Energy Max
  • Enerup Premium
  • Engystol
  • Enhance
  • Enhance9
  • Enhanced Vegetal Vigra capsules
  • Enhancement
  • ENVY BP
  • Eph 100
  • Eph 25
  • Ephedra
  • Ephedra sinica
  • Epio-Plex
  • Epistane
  • Epi-Tren
  • Epivol
  • E-pol Inslinsified
  • ErectMax
  • Eradicate
  • Erex
  • Erexin
  • Erexa
  • Erextra
  • Erexxx
  • Erousa
  • Esbelin siloutte Herbal Blend with L-Carnitine
  • E-Shred
  • Esmeralda softgels
  • ESTRO Xtreme
  • Etumax VIP
  • Ever Slim
  • Everlax
  • Exhilarate
  • Exn
  • Extenze Tablets
  • Extenzen
  • Extenzone
  • Extra Slim Plus Acai Berry
  • Extreme Diamond 3000
  • Extreme Fat Burner
  • Extreme power plus
  • Extreme Stack Fat Burner
  • Extrim Plus
  • Extrim Plus 24 Hour Reburn
  • Eyeful
  • Ezerex
  • Fastin
  • Fasting Diet
  • FASTIN-XR
  • Fat Smack XR
  • Fataway Ultimate Stack
  • Fatloss Slimming
  • Fenfluramine
  • Feng Shi Ling
  • Fenproporex
  • Filix Mas
  • Fina
  • Finabolic 50
  • Finadex
  • Finaflex 550-XD
  • Finaflex Epi V
  • Finaflex Ignite 2
  • Finaflex Limited Edition
  • Finaflex Methyl Ice
  • Finaflex NO Ignite
  • Finaflex Pro Xanthine
  • Finaflex Ripped
  • Finally On Demand
  • Finaplix-H
  • Fire starter
  • Fitropin
  • Flashover
  • Flexile-Plus manufactured by Aspen
  • Fluoxetine
  • For Store Only
  • Forever Beautiful Bee Pollen
  • Forever Beautiful Infinity
  • Forged Burner
  • Forged Extreme Mass
  • Forged Lean Mass
  • Forta For Men products
  • Francis Herb Farm “All Seasons Detox Kit”
  • Francis Herb Farm “Bulklax V”
  • Fresh Lemon Slimming
  • Fruit Plant Lossing Fat Capsule
  • Fruta Bio
  • Fruta Planta
  • Fuel Up High Octabe capsules
  • Fuel Up Plus capsules
  • FuFang
  • Full Throttle On Demand
  • Fung Shing Pai Tian-Ma Wan
  • Furious X 1350
  • Furosemide
  • Fury Extreme
  • FX3000
  • Gat Fornatab
  • Genabol
  • Genesis Ultra Slim Gold
  • Genotropin
  • Geranamine
  • GERMANY NIUBIAN
  • Ginseng Kianpi Pill
  • Ginseng Power-X
  • Ginseng Power 5000
  • Ginseng She Lian Wan
  • Global Dragon Linzi Dong Mai Dan
  • Global Wellness manufactured products
  • Glucobiotic Supreme manufactured by Nutri-Pak
  • GMP
  • GNC “Herbal Plus” Echninacea
  • GNC “Herbal Plus” Gingko Biloba
  • GNC “Herbal Plus” Ginseng
  • GNC “Herbal Plus” Saw Palmetto
  • GNC “Herbal Plus” St. John’s Wort
  • Go On Red
  • Gold Lion
  • Gold Max For Men
  • Gold Max For Women
  • Gold Max Maximum Strength
  • Gold Viagra
  • Gold Viagra capsules
  • Gold Viagra tablets (packaged as “Kangaroo Sexually Invigorating Essence”
  • Golden Night
  • GoldReallas
  • Goodliness Fat-Reducing capsules
  • Goya Bittermelon
  • Gra-MaxX Gold
  • Green Algae
  • Green e
  • Green Lean Body Capsule Super Slim
  • Green stinger
  • Grow Tabs
  • Grow Tabs TR
  • Growth Hormone
  • GTF-Rx
  • Halo For Her
  • Halobolin, manufactured by MyoPharma
  • Halodrol
  • Halodrol Liquidgels
  • Halotestin
  • Halovar, manufactured by Purus Labs
  • Happy Passengers
  • Hard AF
  • Hard Drive
  • Hard Ten Days
  • Hard Wang
  • HCG (Human Chorionic Gonadotropin)
  • H-Drol
  • Health Slimming Coffee
  • Heliotropic supplements
  • Helmi’s Honey VIP
  • Hemo Rage Black
  • Hepatico Extract (Shu Gan Wan)
  • Herb Viagra Male Sexual Stimulant
  • Herbal Health Backplus 500mg
  • Herbal Health JI Special Cream
  • Herbal Health Jointcare
  • Herbal Health RU Special Cream
  • Herbal Health V+
  • Herbal Health XIANG Special Cream
  • Herbal Health YI Special Cream
  • HERBAL VIAGRA
  • Herbal Vigor Quick Fix
  • Herbal Vivid supplements
  • Herbal Xenicol – cetilistat
  • Herbalife Original Green
  • Herberex
  • Hero
  • Higenamine
  • HG4 Up
  • HGH (Human Growth Hormone)
  • High Octane
  • Hi-Tech manufactured supplements
  • HMG Xtreme
  • Hokkaido Slimming
  • Hongkong Tianli Biological ‘Power’ tablets
  • HoneyGizer
  • Honeymoon Exclusive for Men & Women
  • Hot Detox
  • Hot Rod
  • HS Joy of Love
  • Humatrope
  • Hybrid Preamp
  • Hydravax
  • Hydroxa-7
  • Hydroxadrine
  • Hydroxy ripped
  • Hydroxy Stac
  • Hydroxycut with ephedra
  • Hydroxystim
  • Hydroylean
  • Hydroymax
  • Hypercuts
  • Hyperdrol X2
  • HyperleanFX7
  • Hypnos
  • IBU-Relief 12 Cream
  • Idebenone
  • iForce Nutrition manufactured products
  • IGF-1 (Insulin-Like Growth Factor-1)
  • IGF-2
  • Igtropin
  • Imelda Fat Reducer
  • Imelda Perfect Slim
  • Imperial Extreme 2000
  • Imperial Gold 2000
  • Imperial Platnium 2000
  • Imperla Elita Vitaccino
  • IM-Rx
  • Increlex
  • Indian God Lotion
  • iNDiGO
  • Infinity
  • Innerget Everlasting Strength
  • Innerget Instant Erection
  • Innerget Prolonged Performance
  • iNSANE Bee Pollen
  • Instant V-XL
  • Intellux
  • Iowa Select Herbs supplements
  • Iplex
  • IronMagLabs manufactured supplements
  • Isxperia select
  • Ja Dera
  • Ja Dera 100% Natural
  • Jack’D Sexual Enhancement
  • Jack Rabbit
  • Jack3D
  • Jacked up
  • Jaguar Power
  • Jamaican Stone
  • Japan Hokkaido Cangye
  • Japan Lingzhi
  • Japan Rapid Weight Loss Diet Pills Blue – phenolphthalein
  • Japan Rapid Weight Loss Diet Pills Green – phenolphthalein
  • Japan Rapid Weight Loss Diet Pills Yellow – phenolphthalein
  • Jetfire
  • Jetfuel Superburn
  • JETFUEL SUPERBURN by GAT
  • JetFuel T-300 by GAT
  • Jianbu Hugian Wan
  • Jianfeijindan Activity Girl
  • Jiao Shou Shen
  • Jiedu Hugian Wan Tablets
  • Jimpness Beauty Fat Loss Capsules
  • Jin Long Snake Bones Rheumatic
  • JINQIANGBUDOR Red Dragon
  • Jintropin
  • JM Fat Reducer
  • Joint-Soft
  • Joyful Slim – desmthylsibutramine
  • Juiced
  • KaBaNa L-Carnitine 360 Slimming Coffee
  • Kaboom Action Strips
  • Kaizen ephedrine hcl
  • Kangaroo Intense Alpha 3000
  • Kebigutaijiaonang
  • Kilo Sports TrenadrolLiquidrone UTT
  • King of Romance
  • Kingdom Honey Royal Honey VIP
  • Kopi Jantan Traditional Natural Tradisional Natural Herbs Coffee
  • Korvalol products
  • Krazy Night
  • Kwik burn
  • KwikHard
  • Lami Capsules
  • Larry’s Tranquility
  • Launch
  • Lazy Larry Brownies
  • Lazy Larry Cakes
  • L-Carnitine Sob Strengthening Version Slimming Miracle Capsule
  • Lean Body Extreme
  • Lean Efx
  • Lecheek Nutrition manufactured supplements
  • Leisure 18 Slimming Coffee
  • Leopard Secret Miracle Honey
  • Levitra
  • Li Da Daidaihua Plus
  • Li Long Mei Guo Mo Bang
  • Libidinal
  • Libido Edge Capsules
  • Libido Sexual Enhancer
  • Libidus
  • LibieXtreme
  • Libigirl
  • Libigrow
  • LibiMax
  • Libimax X Liquid
  • Libiplus
  • Libipower Plus
  • Lida
  • Lida DaiDaihuaLidiy
  • Life Support
  • Lightning 10.0+ Reduces Weight
  • Lightning Rod
  • Liji Shou
  • Lily Dry
  • Lingzhi Cleansed Slim Tea
  • Lipo-6 Black
  • Lipo-6 Black Hers
  • Lipo-6 Black Hers Ultra Concentrate
  • Lipo-6 Black Ultra Concentrate
  • Lipodrene HARDCORE
  • Lipodrene XTREME
  • Lipopastilla + Gold Max
  • LipoSear
  • Lipotherm
  • Lipozol
  • Lishou
  • Lishou Slimming Coffee
  • Lite Fit USA
  • Liu Bian Li
  • Live Clinical
  • Livtone
  • Liviro3
  • Longue Jambe Frères (Brother Long Legs) tablets
  • Lose Weight Coffee
  • Love Fuel
  • Love Fuel 2
  • Lovers Tea For Men
  • LOVher
  • L-Showm Weight Loss Pills
  • Luvena Prebiotic Daily Therapeutic Wash
  • Luvena Prebiotic Enhanced Personal Lubricant
  • Luvena Prebiotic Feminine Wipes
  • Luvena Prebiotic Vaginal Moisturizer & Lubricant
  • LV Shou Reduces Fat
  • LX1
  • Lycium Barbarum L.
  • Lymphomyosot
  • Lypolysis
  • M1, 4AD
  • Ma Huang
  • Ma huang ephedra
  • Madol
  • Madol
  • Magic for Men
  • Magic Male Enhancer
  • MAGIC PENIS
  • Magic Power Coffee
  • Magic Power Coffee
  • Magic Slim
  • Magic Slim Tea
  • Magic Slim Weight Reduction Capsule
  • Magna Drol
  • MagnaRX
  • Magnum Plus
  • Magnum XXL
  • Mahuang Herbal Ephedra
  • Mahuang RP
  • Majestic Lovezone tablets
  • Male Enhancer
  • Male Silkworm
  • Male V Herbs
  • Mamba Is Hero
  • Man King
  • Man Up Now
  • Manners Energy Boost
  • Mao Slimming Capsules
  • Mas Xtreme Capsules
  • Mass Destruction
  • Mass Tabs
  • MASS Xtreme
  • Massdrol
  • MassiveGrowth
  • Mastavol
  • Master Zone 1500
  • Masteron
  • MataboGold
  • Max Hard
  • Max Male Drive
  • Maxadrine
  • MaxHIMize
  • Maxi Gold capsules
  • Maxidus
  • Maxiloss
  • MaximizeIntense
  • Maximum Horny Goat Weed (all other non-tainted supplements containing horny goat weed are permitted)
  • Maximum Powerful
  • Maxman products
  • MaxOut FX by MaxOut Body
  • Maxrize
  • Maxtremezen
  • Maxyte
  • Mayhem by Chaotic Labz
  • MDIT
  • M-Drol
  • Me36
  • Mecasermin
  • Mechano Growth Factor
  • Medcare Golden Royal Honey
  • Mega Slim
  • MegaJex
  • Megaton 2080
  • Meili
  • Meizi Evolution
  • Meizitang
  • Meizitang Citrus
  • Meizitang Strong Version Botanical Slimming
  • Melanotan – II
  • Merida
  • Mero Macho
  • Mesomorph
  • Metabadrine
  • Metabolic Accelerator by MetaPro 360
  • Metabolic Advantage
  • Metabolife
  • Metabolife EZ Tabs
  • Metab-O-Lite
  • Metabosafe
  • Metaboslim
  • Metaboslim
  • Metabothin
  • Metandienone
  • Methadrol
  • Methandienone
  • MethAnstance
  • Methastadrol
  • Methasterone
  • Methyl Drive 2.0
  • Methyl-1-Testosterone
  • Methyldrene
  • Methyldrostanolone
  • MethylHex 4,2
  • Methylstenbolone
  • Methylsynephrine
  • Mezo
  • Miaozi MeiMiaoQianZiJiaoNang
  • Miaozi Slim Capsules
  • Mince Belle
  • Ming’s Chinese Capsule
  • Miotolan
  • Mira Health manufactured products
  • Miracle Diet 30
  • Miracle Mineral Supplement (MMS)
  • Miraculous Evil Root
  • Miss Slim
  • Mitactin Scabies Treatment
  • Mitotropin
  • Mix Fruit Slimming
  • MMA-3 Xtreme
  • MMC Maxman V Capsules, Maxman IX Capsules and Maxman XI Tablets
  • MMC Sex Men capsules
  • Mojo
  • Mojo Risen
  • Monster Caps
  • Monster Excyte
  • Moska Energy for Adults
  • Motivate
  • Moze Lady products by Mezo
  • MSS Maximum Sexual Stimulant
  • Muscle marinade
  • Muscle Marinade (MM) – Fresh Fruit, Cherry Limeade, Marinade Grape Juice, and Purus Punch
  • Muscle Spike
  • Musli Power
  • MV5 Days
  • MV7 Days
  • MX-LS7
  • My Man His Enhancer
  • Myagen
  • Myoripped
  • N2 Amp
  • Nai Chang Ming Yan Pills (Ming Yan Pills)
  • Napalm
  • Nasty Mass
  • Nasutra
  • Natadrol dietary supplements by LG sciences
  • Natural Balance Cobra
  • Natural Body Solution
  • Natural Max Slimming
  • Natural Max Slimming Capsule
  • Natural Model
  • Natural Passion
  • Natural Vigor Maximum
  • Naturalë Super Plus
  • Natural-Power
  • NaturalUp
  • Natureal capsules
  • NatuRECT
  • Nature’s Science
  • Natur-Leaf
  • Neophase
  • Neophase Natural Sex Enhancer
  • Neuralgo-Rheum
  • NeuRemedy products
  • NeuroCore
  • New Extenze
  • New XZen Platinmun
  • New You Herbal Appetite Suppressant
  • NexGen supplements and topicals
  • NG-Rx
  • Night Bullet
  • Night Man
  • Nine Slim dietary supplements
  • Ninja-X
  • Nite Rider
  • Nite Rider Maximum
  • Nitric Blast
  • Niu Mo Wang ‘Bull Monster’ tablets
  • Niubian
  • Nopal Blood Sugar
  • Norditropin
  • North America Dami Ana
  • North West Wolf capsules
  • Nostrilla
  • Novadex-XT
  • Novedex XT
  • NovoSculpt
  • Noxipro
  • Nutra Coastal Trena
  • Nutracoastal Trena
  • Nutrex Vitrix
  • Nutri Drops Grapefruit Diet
  • NutriBiotic Grapefruit Seed Extract
  • Nutropin
  • NVIE Edge Pro
  • NX-Rx
  • OcuComp manufactured by Atrium
  • Ocu-Comp manufactured by Nutri-Pak
  • Off Cycle II Hardcore
  • OMG
  • OMG45
  • Omnitrope
  • ON Cycle II Hardcore
  • One Weight Loss Pill
  • Opal by Nuway Distributors
  • Opti-Fast
  • OrgaZEN Gold 5800
  • Original Metabolife
  • Original White Dragon
  • OR-Rx
  • Ortiga
  • Ortiga Mas Ajo Rey
  • Ortiga Mas Ajo Rey Extra Forte
  • OstaMax
  • OstaMuscle
  • Ostarine
  • OstaRX
  • Over drive
  • Oxodrol Pro
  • Oxy Elite Pro
  • Oxy-Charge
  • OxyECA
  • OxyElite Pro Super Thermo capsules
  • p57 Hoodia
  • Pai You Guo
  • Pandora
  • Paradise Suplemento Natural Ultra Plus capsules
  • Paranil
  • Passion Coffee
  • P-Boost
  • PC3x
  • PCA-Rx
  • Pe min kan wan
  • Pearl White Slimming Capsules
  • PEB One manufactured by Renutryent
  • PEB Two manufactured by Renutryent
  • Perfect Body Solutions
  • Perfect Combination Balishou Capsule
  • Perfect Slim
  • Perfect Slim 5x
  • Perfect Slim Up
  • Permethrin Cream
  • Phenadrine
  • PhenExtreme by NutraCell Labs
  • Phenibut
  • Phenolphthalein
  • Phenphedrine
  • Phentraburn SlimmingPhyto Shape – rimonabant
  • Phentramin D
  • Phenyldrene Xtreme
  • Phenytoin
  • Phera-Mass
  • Pheravol-V
  • Phreak
  • Phuk
  • Picamilon
  • Pigmento
  • Pil Raja Urat Asli
  • Pineapple Fat Reducing Slimming Capsule
  • Pink Pussycat
  • Placenta Lucchini
  • Plant Vigra
  • Play Hard For Men
  • Pleo Homeopathic products
  • Plexus Slim Accelerator 3 Day Trial Pack
  • Plexus Slim Accelerator Capsules
  • PN-Rx
  • Poseidon Platinum
  • Potion 9
  • Power 1
  • Power Source Maxxx
  • Powerful Slim
  • Powermania
  • Power-X
  • P-Plex
  • Premier Platinum 5000
  • PremierZen
  • Premium OrgaZen 7000
  • PrePost
  • Primilut N
  • PrimeZen Black 6000
  • Primobolan
  • Pro ArthMax
  • Pro Plus Xtreme
  • Pro Solution Gel and Pills
  • Pro Stanivar
  • Pro V Xtend
  • Proactin_Syrup
  • Prolatis
  • Prolifta Capsules
  • Promatrix DHEA 25
  • Propell Platinum
  • Propranolol
  • ProSlim Plus
  • Protropin
  • Proviron
  • PR-XT Advanced
  • Pure Caffeine Powder
  • Purple Tiger
  • PWR
  • Quake 10.0
  • Que She – fenfluramine; propranolol; sibutramine; ephedrine
  • Quickslim-30
  • R1881
  • Race Caps Supreme
  • Rage
  • Rainbow Rocket
  • Rapha Diet
  • RAPHA Vitamin B1
  • Rapid Action Energize
  • Rapid Release
  • Razor8 Blast Powder
  • Real Deal
  • Real Deal ECA-Stack
  • Real Skill
  • Recombinant
  • Red devils
  • Red Hot Sex
  • Red Magic
  • Red Mammoth
  • Red Spartan 3000
  • Red Spider 5ml
  • Red Stinger Black Label
  • REDDIES
  • Redline Black Diamond
  • Redline Black on Blue V2
  • Redline Ultra Hardcore
  • Redline Xtreme Energy Drink
  • Reduce WeihgtWeight
  • Refresh Green
  • Regen Arouse
  • Regen Erect
  • Regenerect
  • RegeneSlim
  • Renuvetrol
  • Reparil
  • Revalor-H
  • Revalor-IS
  • REVALOR-XS IMPLANT 100DS SO
  • Revamp
  • Revenge
  • Reversitol
  • Revivexxx
  • Rezolution
  • RezzRX
  • Rhino products for male enhancement
  • Rimonabant
  • Ripped force
  • Ripped Juice
  • Ripped Stack
  • Ripped Tabs TR
  • Riptek V2
  • Rise Up
  • Rize 2 The Occasion
  • Robust
  • Rock Hard
  • Rock Hard Extreme
  • Rock Hard Weekend
  • Rock It Man
  • Rock Steady 72 Hours
  • Rockhard
  • Rose 4 Her
  • Royal Honey
  • Royal Slimming Formula
  • RSe7en
  • RV2
  • RV3
  • RV4
  • RV5
  • Rx_erect
  • S Lion Juice 1
  • S.W.A.G.G.E.R Extreme
  • Saizen
  • Salute
  • Samurai-X
  • San Xiao Ping Tang Jin Qi Jiao Nang
  • Sana Plus
  • Sangter
  • Sanovera Starter capsules
  • SanPharma products
  • Santé FX Neo
  • Santé FX Neo
  • Santé FX V+
  • Santé FX V+
  • Santen eye drops
  • Santi Scalper
  • Sci-Fit
  • S-Drol
  • Secret Miracle Honey
  • Seirogan Toi A
  • Semenax
  • Serostim
  • Seven Slim
  • Sex Drive Capsules
  • Sex Enhancer
  • Sexamax
  • Sex-Love Secret Code capsules
  • Sexo_Loco
  • SexRX
  • Sextra
  • Sexual Surge
  • Sexy Monkey
  • Shangai Regular
  • Shangai Regular, also marketed as Shangai Chaojimengnan
  • Shangai Ultra
  • Shangai Ultra X
  • Sheng Jing Pian
  • Sheng Yuan Fang
  • Shengjingpian
  • Shi Hu Ye Guang Wan (Ye Guang Wan)
  • Shogun-X
  • Shorts on the beach by Lucy’s Weight Loss System
  • Shoufsy Activity Girl
  • Shree Baidyanath brand
  • Shwasa Sanjeevani
  • Sibutramine
  • Sit and Slim II
  • Six Spirit Pills (Liu Shen Wan)
  • Size Matters
  • Skinny 22
  • Slender Slim 11
  • Slender-Mist Sprays
  • Slim 3 in 1
  • Slim 3 in 1 Extra Slim Formula
  • Slim 3 in 1 Extra Slim Waist Formula
  • Slim 3 in 1 M18 Royal Diet
  • Slim 3 in 1 Slim Formula
  • Slim Burn
  • Slim Easy
  • Slim Expert
  • Slim Expert
  • Slim Express (ผอมขั้นเทพ)
  • Slim Express 360
  • Slim Express 4 in 1
  • Slim Fast
  • Slim Forte Slimming Capsules
  • Slim Forte Slimming Coffee
  • Slim Fortune
  • Slim Fortune
  • Slim Gram
  • Slim Max
  • Slim Perfect Arm
  • Slim Perfect Legs
  • Slim Quick Result 3 in 1
  • Slim Tech
  • Slim Trim U
  • Slim Up
  • Slim Vie
  • Slim Waist Formula
  • Slim Waistline
  • Slim Xtreme
  • Slim Xtreme Herbal Slimming Capsule
  • Slim-30
  • Slimbionic
  • SlimDemand Capsules
  • Slimdia Revolution
  • SlimEasy Herbs Capsules
  • SlimExtra Herbal Capsules
  • Slimfast
  • Slimina weightloss capsules
  • Sliminate
  • Sliming Diet Berry Plus
  • Slim-K manufactured by Bethel Nutritional
  • Slimming Beauty
  • Slimming Diet
  • Slimming Diet by Pretty White
  • Slimming Formula
  • Slimquick Green Coffee Bean Softgel
  • Slyn Both
  • Slyn Both Green capsules
  • Smoking Cessation Aid
  • Solcoseryl
  • Solo Slim
  • Solo Slim Extra Strength
  • Soma
  • Somabolin
  • Somatomedin
  • Somatotrophin
  • Somatotropin
  • Somatrem
  • Somatroph HC
  • Somatropin
  • Somotrim
  • Sonar manufactured products
  • S-organic Cocoa+L-carnitine
  • Source Naturals Male Response
  • South America Maca (all other non-tainted supplements containing maca are permitted)
  • Sparta X
  • Spascupreel
  • Spawn
  • SPCARET Princess Diet
  • Spectrazyme – chloramphenicol
  • Speed V2
  • Spirodene
  • Spirodex
  • Sport Burner
  • Sport X Ephedrine
  • S-shape slim capsules
  • Sta Max Plus
  • Stamina-Rx
  • Staminil
  • Star Majestic
  • Starcaps – bumetanide
  • Star-SX Gold
  • STB Summit of the Thin Body S Woman Degreasing Burning Pill
  • STEAM
  • Steel Libido
  • Stenbolone
  • Sterodrol
  • Steroids
  • Stiff Days
  • Stiff Nights
  • Stiff One Hard 169
  • Stiff Rocks products
  • Stim Force
  • Stimerex es
  • Stimerex-ES
  • Stimuloid II
  • Straight Drol
  • Straight Phlexed
  • Straight Up
  • Stree Overlord
  • Strombafort, Winstrol
  • Strong Horses capsules
  • Strong Testis
  • Strong_Man_Bao
  • Strong-SX
  • Stron-SX capsules
  • Stud Capsules
  • Sudibil-Xr
  • Sulami
  • Super Arthgold
  • Super Bull 6000
  • Super Cal-Pro Powder
  • Super Caps
  • Super Dragon 6000
  • Super Ephedra Extreme
  • Super Extreme Accelerator
  • Super Fat Burner
  • Super Fat Burning
  • Super Fat Burning Bomb
  • Super Hard
  • Super Herbs
  • Super Lean 1000
  • Super Panther 77k
  • Super Power
  • Super Shangai
  • Super Slimming
  • Super Tiger-X
  • Super Tren
  • Super-DMZ Rx 3.0
  • Superdrine
  • Superdrine RX-10
  • Superdrol
  • Super-Flex manufactured by Atrium
  • Superior
  • Superslim
  • SuppressNT
  • Surge XMP
  • SUS-500
  • Sustamed, Sustanon
  • Sustenol 250
  • Susto-Test Depot
  • Svelte 30 Capsules
  • Swagger
  • Synedrex
  • Synovex Choice implants
  • Synovex Plus implants
  • Syntrion productsTraumeel
  • Tacktol
  • Tan Bee Pollen
  • Tanning pills containing canthaxanthin
  • Tantra Jelly Herbal Jelly for Him
  • Target “Up & Up” Gingko Biloba
  • Target “Up & Up” St. John’s Wort
  • Target “Up & Up” Valerian Root
  • Tawon Liar
  • Tenfold
  • Tengda
  • Testosterone Cream for Men
  • Testosterone Cream for Women
  • Testra-Flex
  • Tev-Tropin
  • THE BEST Enhancement Supplement
  • The Clear
  • The Natural Alternative by Thin and Slim Naturally
  • The Pink Bikini by Lucy’s Weight Loss System
  • The Razor’s Edge
  • The Rock
  • Thermbuterol
  • Thermo speed
  • Thermo trim
  • Thermoburn
  • Thermofuse
  • ThermoFX by The People’s Chemist
  • Thermogen II
  • Thermogenic Fat Burner by The Store
  • Thermogum
  • Thermojetics Original Green
  • Thermolean
  • Thermra Epimedyumlu Bitkisel Karismli Macun
  • Thinogenics
  • Thumbs Up 7
  • Thyriod Gland by Life Choice Ltd.
  • Thyroid
  • Thyroid extract
  • Tianeptine
  • Tian Ma Toutong Wan
  • Tianji True Slim
  • Tibet Babao
  • Tiger King
  • Tip-Top Shape supplements
  • Titanium 18k
  • TNT Thermanite
  • Tomato Slimming
  • Tongqiao Biyan Pian
  • Tonic Life BP – phenolphthalein
  • Top Man 3
  • Topviril
  • Toxin Discharge Tea
  • Train
  • Tren
  • Tren-250
  • Trena
  • Trenabol
  • TrenadroI-X
  • Trenadrol
  • Trenavar
  • Trenavar
  • Trenbolone
  • TREN-Xtreme
  • Tri-Methyl X
  • Tri-Methyl Xtreme
  • Trim-Fast Slimming Softgel
  • Triple Extenzen
  • Triple MiracleZen Platinum
  • Triple PowerZEN Gold
  • Triple Slim
  • Triple SupremeZen
  • Triple Wicked Platinum 
  • T-Roid
  • Trojans Horse Man Power
  • tru Weight & Energy + truFIX
  • True Man
  • True Man Sexual Energy
  • TruTrim or Tru-Trim weight loss products
  • TT-40-Xtreme
  • Tummy Tuck Max
  • TUPMAX
  • Turanabol
  • Turbo charge
  • Turinabol
  • Turnivol
  • Ubervita products
  • Udep
  • Ultimate
  • Ultimate Antioxidant
  • Ultimate Boost
  • Ultimate Formula Capsules
  • Ultimate Herbal Slimcap capsules by Fit Firm and Fabulous
  • Ultimate orange
  • Ultra Mass Stack
  • Ultra Pure Yohimbe
  • Ultra SX Capsules
  • Ultra ZX
  • Ultra-AV
  • Ultracuts
  • Ultradrol
  • Uprizing 2.0
  • USA Gold Ant capsules
  • USA Viagra
  • USP Labs manufactured supplements
  • V Max
  • V26 Slimming Coffee products
  • V8 Energy
  • Valtropin
  • Vanish containing BMPEA by Pro Supps
  • VasoprophinRX
  • Vaxitrol
  • Velocity XT
  • Vengeance by UG Pharma
  • Venom hyperdrive
  • Venom Hyperdrive 3.0
  • Verect
  • VERSA-1 – aegelineloss
  • Via Xtreme Ultimate
  • ViaFem
  • Viagra
  • Viagra 007
  • Vialipro
  • Viaplus Gold
  • Viapro
  • ViaXtreme
  • Vicerex
  • Vierect
  • Vigor 800
  • Vigor Tea Sachets
  • Vigor-25
  • Vigour 300
  • Vigorous Man
  • Vigra
  • VIM25
  • Vimax
  • Vine Essence
  • Virilis Pro
  • Virility Max
  • Viril-Ity Power (VIP) Tabs
  • Virility VPRX
  • Virmax DS
  • Vitaccino coffee
  • Vital Honey
  • Vital Sex
  • Vitalikor Fast Acting
  • VitaMineral Earth
  • VitaMineral Green
  • Vitapril
  • VNS-9 Xtreme
  • Volcano Male
  • VolumePills
  • VPRX Oil
  • Vswiss
  • Vy & Tea
  • W.A.G. Sex with a Grudge
  • W.-W
  • Waist Strength Formula
  • Walgreens “Finest Nutrition” Echinacea
  • Walgreens “Finest Nutrition” Garlic
  • Walgreens “Finest Nutrition” Gingko Biloba
  • Walgreens “Finest Nutrition” Ginseng
  • Walgreens “Finest Nutrition” St. John’s Wort
  • Walmart “Spring Valley” Echinacea
  • Walmart “Spring Valley” Garlic
  • Walmart “Spring Valley” Gingko Biloba
  • Walmart “Spring Valley” Ginseng
  • Walmart “Spring Valley” Saw Palmetto
  • Walmart “Spring Valley” St. John’s Wort
  • Warrior Force “Warrior Core Foundation” and “TruGanic”
  • Warrior Force “Warrior Endurance”
  • Warrior Force “Warrior Greens” Vegan Caps
  • Weekend King
  • Weekend Prince
  • Weekend Warrior
  • Whacked out
  • Whatzup
  • White Panther
  • Wild Sexx
  • Wonderful Honey
  • Wood-E
  • WOW
  • Wyked
  • X Rated Honey
  • Xcel
  • Xcel Advanced
  • Xcellerator weight loss products
  • Xenaclen
  • Xenadrine rfa 1
  • XenaleanPro
  • Xerophagy
  • XForMan Plus
  • X-Hero
  • Xiadafil VIP Tabs
  • Xiatrex
  • XM3
  • Xplozion
  • X-Rock
  • Xsvelten
  • Xtra Innings
  • Xtremexcite
  • X-Tren
  • X-TRN
  • XXX Platinum Woodie
  • Xytamax
  • Xytomax
  • XZone Gold
  • Y-4ever
  • Yanhee Slim
  • Yellow bullet
  • Yellow cross
  • Yellow Devils
  • Yellow haze
  • Yellow jacket
  • Yellow power
  • Yellow Scorpion
  • Yellow scorpion
  • Yellow subs
  • Yellow swarm
  • Yilishen
  • Ying Da Wang
  • Ying Dao Di capsules
  • Yin-Yang Essence Men Power
  • Yohimbe Erection Lotion
  • Yong Gang
  • Youth_Addict
  • Yunnan Baiyao
  • Zan-X Extra Relaxation
  • Zeel
  • Zencore Plus
  • Zenerect
  • Zenerx
  • Zeri Xtreme Capsules
  • Zero Fat
  • Zero Xtreme
  • Zhen de Shou
  • Zhen Gong Fu
  • Zhen Gongfu
  • Zhong Hua Niu Bian
  • Zhonghua Niubian
  • Zi Xiu Tang Bee Pollen Capsules (also known as “ZXT Slim Bee Pollen”)
  • Ziapro
  • Zilex
  • Zimaxx
  • Zing Plus
  • ZlimXter
  • Zolpeadem
  • Zomacton
  • Zoom-Zooma-Zoom
  • Zorbtive
  • Zotrex
  • ZR dietary capsules
  • ZXT Gold
  • ZXT Gold Infinity
  • Zyogin
  • Zyrexin
  • Zytenz

New Research and Opportunities in Weight Management

by NaturPro in Uncategorized Comments: 0

Untold tens of thousands of published scientific studies reveal ways to maintain a healthy body weight. Most weight management studies published in the past 20 years heavily emphasize overall diet and lifestyle, incorporating lifestyle interventions in addition to drugs or supplements.

Simple lifestyle interventions—like getting a daily text reminder, recording an eating diary, and attending group meetings or therapy—are shown to help lose some weight. Yet on average, the weight lost with most simple interventions (no extreme calorie restriction or drug or supplement intervention) is usually small—in the range of 5 to 10 pounds over a course of three to 12 months, depending on the study.

Over the longer term, the numbers are worse. Folks often rubber band as far the opposite way as they came. Either way, many rigid plans over the long term are enough to reverse obesity and improve health outcomes for most individuals. Overweight individuals often need a little more help to reach a healthy weight.

But these days, marketing supplements to support weight management goals is tough, and depends more than ever on how a product is developed, studied and labeled. Intense regulatory scrutiny of weight loss supplements has all but decimated the use of the word “loss.” Now, products historically marketed for “weight loss” are instead touting “weight management,” and making no numerical claims about pounds or body mass index (BMI) lost. It’s hard to tell how well these claims resonate with consumers.

Natural Product Consultants

The bar to make more aggressive and meaningful claims has been set high in recent times by FTC, which requires repeated, well-designed, rigorous clinical studies that stand up to scrutiny. Lower-risk approaches are frequently recommended, to include carefully worded marketing and labeling. Adding qualified claims and disclaimers on weight management products can serve to both educate consumers as to what they should do outside of taking a supplement—and also warn them that a pill will not cure couch potato-itis. Today’s savvy consumers know that miracle diets are unbelievable, because many of the more successful weight management regimens in recent years have included nutritional products within a lifestyle plan, such as diet guidance, food lists and other helpful tools.

In that context, let’s talk about some of the supplements shown to be helpful for weight loss, supplements shown to be helpful for weight loss especially as part of a healthy diet and lifestyle:

Whey protein: It makes sense that protein intake can replace carbs and fat and help to increase muscle mass. But science is starting to figure out other ways in which protein works for healthy body weight. A 2022 study in older overweight or obese women found that adding 20 grams of whey protein or whey protein hydrolysate to an energy-restricted diet for eight weeks reduced body fat and upregulated key metabolomic pathways compared to the restricted diet alone. On the protein note, another 2022 study found that unprocessed red meat in overweight/obese adults after a rapid weight loss further reduced body fat and increased lean muscle mass.

Omega-3 fatty acids: Polyunsaturated fatty acids (PUFAs) are important nutrients that play a role in body lipids and inflammation. Studies have suggested that supplementation with omega-3 can help reduce body weight. A recent study in middle-aged, overweight adults found that 1,020 mg omega-3s for 12 weeks lowered abdominal fat versus the placebo group.

Licorice extract: Studies on nonalcoholic fatty liver disease (NAFLD) may offer some clues of interventions that may also be helpful for weight loss. Because NAFLD and obesity are heavily associated, improving markers of one often leads to an improvement in the other. In one study in women with NAFLD, women who took 1,000 mg licorice extract a day as part of a weight loss diet experienced improved markers of NAFLD, versus those who only engaged in a lifestyle intervention. More research is needed to determine the potential effects of licorice on body weight.

Synbiotics: Some subpopulations of humans are more prone to gain excess weight. In a recent study on people experiencing weight gain due to antipsychotic use, those who took probiotics with dietary fiber reduced body weight and metabolic abnormalities.

Antioxidants: Natural antioxidants from fruits, vegetables and spices show promise, because they tend to support metabolic function and help to balance inflammation associated with stress and being overweight. A study on Moro blood orange extract improved BMI, fat mass, and hip and waist circumference in healthy, overweight adults after six months, versus placebo.

Calcium and vitamin D: Combining calcium with vitamin D and low-fat dairy products as part of a hypocaloric diet was recently shown to improve blood lipids, leptin and apolipoprotein B (ApoB, involved in lipid metabolism). Both calcium and vitamin D are essential to metabolic function, and a large percentage of American adults are at least moderately insufficient in this nutrient pairing.

Natural GLP-1 agonists: One main emerging biological pathway interesting for weight loss drugs and supplements is glucagon-like peptide-1 (GLP-1). Semaglutide (Ozempic) is one of the notable drugs that increases the expression of GLP-1, which reduces feelings of hunger and food intake, resulting in significant weight loss. However, this class of drugs is associated with side effects and the unknowns of long-term use. Several natural products also appear to act as GLP-1 agonists, some of which are traditionally used to support healthy metabolic function. Examples of GLP-1 agonists in the diet include:

• Hops extract (500 mg) in both fast and slow-release forms stimulated secretion of lunchtime GLP-1, as well as ghrelin and peptide YY, compared to placebo.

• Eriocitrin (200 mg as Eriomin, from Ingredients by Nature) is an antioxidant flavonoid from lemons which in a 2022 study increased GLP-1 while decreasing blood glucose and tumor necrosis factor (TNF)-alpha in people with moderately high blood sugar.

• Isomaltulose is an alternative sugar which does not spike blood sugar like other sugars. In a 2019 study, isomaltulose increased GLP-1 by up to 85% compared to sucrose or table sugar, while decreasing blood sugar and insulin in healthy, impaired glucose and type 2 diabetic adults.

Supplement capsules prototype pilot samples

Looking at the recent literature, measurement of markers like GLP-1 has increasingly become standard in weight management trials. It’s only a matter of time until some supplements are validated in rigorous, large studies with well-designed dietary interventions proven to accelerate weight loss and support healthy weight management for the long term.

Reflecting on the kinds of supplements being studied versus the dietary recommendations supporting a healthy body weight, a lot is shared in common: antioxidants, fiber, micronutrients and healthy fats are considered part of a healthy diet more now than ever.

But as everyone knows, it’s hard to get enough of these nutrients from foods alone. So these days, when I sit down with my parents for a family meal, I’m bringing some supplements.

This article was originally published in the April 2023 Natural Products Insider Digital Magazine.

What’s ‘noo’ in nootropics?


Well first: what’s NOT new: Pharmaceutical ingredients masquerading as nootropic supplements. A February 2019 Warning Letter from FDA to Pure Nootropics LLC regarding disease claims for legitimate supplements, along with drugs sold as supplements (like piracetam and its analogs) was followed by a polite closeout letter in June of that year, failing to mention whether said ingredients are actually dietary ingredients. The takeaway? Unapproved drugs are regulated just like all the legal dietary ingredients, as long as you don’t claim it prevents or cures disease. 

Brain Supplement Nootropic Food Beverage Drink

What a missed opportunity to draw the line between dietary ingredient — and totally not one! Now, the deluge of -racetams and analogs of unapproved drugs continues. Because after aniracetam comes johnnyracetam and billyracetam, according to our historically accurate crystal ball. So much for the well-regulated vitamin militia.

Luckily, there’s a lot of safe and natural ingredients in food that boost brain power. Choline, the building block of neurotransmitters now no longer “conditionally” essential, but fully essential at a recommended amount of 550mg per day. Choline is the place where nootropics and nutrition meet. Recent work has shown that phospholipid-bound choline from food sources like egg absorb around 4 times better than choline bitartrate salt. Maybe no surprise, since the egg came first — but the chicken is crossing the road too. Recently, hydrolyzed chicken essence peptides improved memory in people with stress.

Astaxanthin Fish Seafood Antioxidant

Evolving science is starting to consider effective combinations of antioxidants to improve brain function. As we know, the brain burns hot with energy, at the expense of a lot of waste byproducts – a lot of oxidative stress.  So we could look at ingredients like astaxanthin, the super-powered antioxidant from the deep sea, as a kind of base ingredient from which to expand. Conventional wisdom, enabled by improved clinical methods, suggests that combinations of ingredients can be helpful to exert an effect on the brain beyond simply “antioxidant activity”. Cerebral blood flow, brain waves and validated clinical instruments for cognitive function lead the way, so we can drill down more precisely on nootropics’ effects on the brain. 

Recently, we have studies on astaxanthin and tocotrienols or sesamin shown to improve cognitive function and perform complex tasks quickly and efficiently. And in 2020, a polyphenol-rich beverage with apple polyphenols, ginseng and coffee berry extract improved cognition, mood and cerebral blood flow in a randomized controlled human trial.  I’m looking for new product launches inspired by the science on studied combinations to provide synergistic mental gains, compared to any one ingredient alone. That means more finished product marketers need to invest in studies on their products. 

Dietary flavanols, like those from cocoa, are being increasingly studied for the brain. Like with many supplements, clinical results from cocoa flavanols on the brain have been mixed. But we know one of the reasons why – because results are confounded by scientific and practical limitations of clinical measurements and study design. For example, if all your study has is a ruler marked to the nearest inch, then you can’t use the ruler to measure millimeters — or time, for that matter. In a new study, researchers found that the cognitive benefits of cocoa flavanols — likely due to increased blood flow to the brain — occurs mainly in people who have inadequate blood oxygenation to start with. Clinical trialists are starting to understand that every human is different, and that to avoid another null or confusing result, they need to more carefully select the trial subjects who are most likely to benefit from a nutritional intervention. 

Coffee fruit ingredient specification supplier

Science is also investigating alternatives to caffeine. While we love our morning joe, chock full o’ xanthine alkaloids, we also can’t escape the jitters, cortisol spike and crash that comes with the daily mainline. The emergence of low- and no-caffeine products to boost brain power are likely to deliver on benefits where caffeine cannot – more sustained energy, less stress, better sleep and recovery, no habituation, and a refreshing start to the next day. So that in the future, maybe we’ll prefer to wake up to a triple shot of green oat espresso

Speaking of refreshing starts, it’s well established that sleep quality is directly correlated with next-day mental and physical performance. So it makes sense that supplements that truly improve sleep and stress levels are likely to improve brain power as well. A low-sugar drink with tart cherry, protein, valerian and L-theanine improved some markers of sleep without detrimental effects the next day. I’m looking for more products that you consume today, to be more productive and healthy, and less stressed tomorrow. 

Many traditional remedies used for relaxation have been studied for improved cognitive function. Essential oils, once the black sheep of evidence-based health, are getting a new look. Lamiaceae, the marvelous mint family of botanicals that includes lavender, rosemary, lemon balm and sage, is being tapped to induce relaxation and improve mental function. Recently, a small, 100 microliter oral dose of peppermint oil rich in menthol and menthone improved information processing and lowered mental fatigue in demanding cognitive tasks. Combinations of other botanicals from this family are also being studied for improved cognitive function.

food supplement product development

And finally, the 2021 award for most-overlooked-but-recently-studied nootropic ingredient is…. Plain old water. It makes up 73% of your brain. It’s cheap. Safe. And it is unquestionably not a drug in disguise. In recent studies, water improved memory in kids. In another study in young adults, a small amount of water (200 mL) was enough to improve mood and fatigue, but only the higher dose of water (500 mL) improved working memory

So when it comes to nootropics, maybe it’s time to throw away the billyracetam, and enjoy a cool drink of H2O instead.  

Sustainable sourcing: Not ‘selfies with farmers’

by NaturPro in Uncategorized Comments: 0

International standards and regenerative farming are at the leading edge of sustainability when discussing the sourcing of herbs and botanicals. But at essence, promoting sustainability begins with evaluating and understanding what is needed most to sustain and improve supply.

Toxins land baby foods in hot water

by NaturPro in Uncategorized Comments: 0

Ebersole can see the writing on the wall. “I expect the media will report that these levels reported in baby food are toxic—and sow more distrust in baby food. Meanwhile, industry looks bad, but it’s not entirely our fault without some clarity on what limits we should be setting,” he said.

How to Meet Amazon Supplement COA (Certificate of Analysis) Requirements


Understanding Amazon’s new requirements for supplement testing can be hard, but we can help.

We are aware of the rapidly changing, uncertain requirements of Amazon for dietary supplements.

One of the key new requirements is for marketers to submit certificates of analysis, of COA for many dietary supplement products.

As of late 2020, Amazon.com is now requiring many supplement products to submit lab reports as evidence that their products are independently tested and meet label claims for active ingredients listed on the label.

There is no ‘one-size-fits-all’ solution to testing, COA’s or meeting Amazon requirements, so its important to evaluate your product testing program, and improve it so you can stay on the Amazon selling platform.

Contact us to learn more about how to ensure you are meeting Amazon requirements.

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Here is a handy checklist of some of the main requirements for information now required by Amazon for many supplement products, in order to be approved for sale on the Amazon platform:

  1. Product name
  2. Lot number
  3. Manufacture date
  4. Valid expiration date, or ‘best by’ date
  5. Name and physical address of manufacturer or distributor
  6. Testing Lab method is scientifically valid, and the lab reports (Lab Certificates of Analysis are complete, and issued from an ISO 17025 certified laboratory within the past 6 months
  7. The COA contains a quantitative analytical result that supports the concentration of active ingredients stated on the supplement product label.

These are items that many sellers (and even FDA) has overlooked in the past. Considering the importance of Amazon to the supplement industry, these new requirements could determine which supplement marketers, or own-label distributors, are going to survive in the new world of stricter requirements on the Amazon website.

ABOUT US:

NaturPro Scientific are experts in label review, supplement testing and COA’s, and we can help you make sure you are compliant with Amazon’s latest requirements.

Contact us to learn more about how to ensure you are meeting Amazon’s document and testing requirements for dietary supplements.

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And for more info, check out some of our FREE articles on supplement label requirements:

Dietary Supplement Label Review

Supplement Label Review Checklist

Dietary Supplement Quality Assurance Services

How to Know the Regulatory Status of Your Ingredient

Supplement Testing Lab and Testing Method Qualification