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NaturPro Verified Supply

As consultants for a diversity of supplement and food firms, NaturPro Scientific has qualified numerous ingredients, suppliers and products.

So, we decided to share some of the products and ingredients that we have verified as a curated list: NaturPro Verified Supply™

What’s different about NaturPro Verified Supply compared to typical product listings?

  1. Suppliers cannot pay to be listed. NaturPro does not accept fees or commissions to represent or promote any specific ingredients or products. 
  2. Our core business is in vetting the best ingredients and products — not selling them. We are not tied or committed to any one ingredient or supplier, so we can keep our standards high.
  3. Our vetting process goes beyond FDA regulatory requirements. NaturPro standards include our intimate understanding of product safety, claims substantiation, supply chain quality, sustainability, GMP’s and traceability.
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Muscadine Grape Extracts and Concentrates (Southeast USA)
$90/kg+
Muscadine Grape Extracts and Concentrates (Southeast USA) Image

HARVEST SUPPLY AVAILABLE:

  • Sweet, tart and astringent all at once
  • 10-20x more resveratrol than red wine
  • Single source, US grown
  • Full-Spectrum Antioxidant Ingredients:
    • Ultra-premium muscadine wine concentrate — equal to 22 glasses of red wine!
    • Powdered extract – dried seed & skin (spray dried)

LIMITED SUPPLY – CONTACT US


And a little background why we love muscadines…

Why are Muscadines Special?

  • 40 times the antioxidant power of table grapes
  • 6 times the resveratrol of table grapes
  • The only grape with ellagic acid and ellagitannins
  • Abundant levels of flavonoids, including quercetin

Few traditional fruits are a staple to local culture like muscadine grapes are in the American South.

First cultivated and consumed by Native Americans for hundreds of years, muscadines (Vitis rotundifolia Michx.) go by many names originating from the first tribes, including scuppernongs, bullets, or bullises.  Muscadine is also known in various parts as bull grape, bullet grape, or Southern fox grape.

Muscadine Grape Ingredients

Muscadine grape ingredients work for supplements, foods and beverages, with the resveratrol of 22 glasses of wine.

Muscadines are highly researched and widely consumed in the U.S. More than 100 preclinical and clinical studies have been published on muscadines! And, thousands more studies have evaluated the potential health benefits of the antioxidant molecules found in muscadine.

Muscadine nutrients are in food-bound form, which means they’re bioavailable and better absorbed into cells. And studies show muscadines are more effective at quenching free radicals compared to isolated antioxidants like vitamin C and quercetin at quenching free radicals.

In addition to the high content of antioxidants in Muscadine grape products and extracts, compounds in Muscadine also stimulates the body’s own antioxidant protection mechanisms.

Muscadines’ whole-food synergy was confirmed when studies found it may stimulate both types of antioxidant defensesin the body — exogenous and endogenous. (Most antioxidants only support a limited number of antioxidant pathways).

The polyphenol-preparation from Muscadine grape was tested in a blend with chemically pure resveratrol.The blend containing Muscadine polyphenols reduced the inflammatory response to a test meal, in part via the induction of genes involved in production of antioxidant enzymes, called “Antioxidant Response Elements (ARE)”, These include genes, such as Nrf-2, that regulate the expression of antioxidant proteins that protect against oxidative damage triggered by injury and inflammation,

Muscadine grape polyphenols contribute to the regulation of our genes to increase our body’s own antioxidant protection, beyond the antioxidants in the grape itself.

The various health benefits of muscadine have been studied in clinical and preclinical trials. Some of the areas of health areas studied include:

  • Potent Antioxidant; Supports Body’s Antioxidant Defense
  • Energy and Mitochondrial Biogenesis
  • Healthy Aging
  • Cardiovascular Support & Healthy Blood Pressure
  • Men’s Health & Prostate Health
  • Healthy Metabolism
  • Brain and Cognitive Health
  • Sports Nutrition
  • Liver Support, Detoxification
  • Inflammation

​For these reasons, Muscadines, also known as “Super Grapes” are expected to be the ultimate anti-aging food for this century!

Synergy From Multiple Classes of Polyphenols in Muscadines 

Polyphenols from foods are widely studied to support the function of brain, heart, liver, joints, muscle recovery, and other organs. As antioxidants, they support the body’s cellular function and recovery from normal metabolism, and reduce oxidative stress and inflammation associated with many disease states.

Muscadine’s polyphenols are unique because they contain both resveratrol and ellagic acid, two antioxidants that are found in red wine, pomegranate and berries. Resveratrol is a well-researched antioxidant that is shown to extend lifespan in animals, act on mitochondria to improve metabolic function, and possess a number of beneficial activities when consumed.  Ellagic acid and gallic acid, plus the polyphenolic tannins from which they are derived during ripening and processing, are potent antioxidants that have diverse metabolic and inflammation-mediating activities.

Muscadine also contains flavonoids such as anthocyanins and quercetin, which lend a purple-red or yellow hue to the fruit, respectively.  Catechin flavonoids such as epicatechin, epicatechin gallate, and proanthocyanidin tannins are also found in the fruit, mainly in the seed.

Primary muscadine polyphenols include:

  1. Resveratrol, a well-researched antioxidant that is shown to extend lifespan in animals, acts on mitochondria to improve metabolic function, and possess a number of beneficial activities when consumed.
  2. Ellagitannins, including ellagic acid and gallic acid, are potent antioxidants that have metabolic, anti-inflammatory and anti-cancer activities.
  3. Muscadine also contains flavonoids such as anthocyanins and quercetin, which lend a purple-red or yellow hue to the fruit, respectively.
  4. Catechin flavonoids such as epicatechin, epicatechin gallate, and oligomeric proanthocyanidin tannins are also found in the fruit, mainly in the seed.

Muscadines are very high in antioxidant capacity relative to other antioxidants. This data, along with the limited clinical evidence, supports strong antioxidant claims for muscadine:

Whole Muscadine Fruit Extract – 23,000
Muscadine Seed Extract – 17,000
Grape Seed Extract (Conventional) – 11,000
Whole Muscadine  Fruit Powder – 3,000
Muscadine Fruit Skin – 5,000
Muscadine Seed – 4,000
Muscadine Juice Concentrate – 4,000
Acai powder – 1027
Bilberry, dried – 500
Elderberry – 150
Cranberry – 90
Plums – 85
Blueberry juice – 24
Concord grape juice – 24
Grape juice, red – 18
Grapes – fresh black – 17
Grapes – fresh red – 18
Green tea, brewed – 13

Reference: Total ORAC Data from USDA ORAC Database (2010). The cited 2010 data for Total ORAC was separated into 2 assays: hydrophilic and lipophilic. Muscadine ORAC data is the sum of six ORAC subtests. 

 

Ingredients
Muscadine Grape Extracts and Concentrates (Southeast USA)
$90/kg+
Muscadine Grape Extracts and Concentrates (Southeast USA) Image

HARVEST SUPPLY AVAILABLE:

  • Sweet, tart and astringent all at once
  • 10-20x more resveratrol than red wine
  • Single source, US grown
  • Full-Spectrum Antioxidant Ingredients:
    • Ultra-premium muscadine wine concentrate — equal to 22 glasses of red wine!
    • Powdered extract – dried seed & skin (spray dried)

LIMITED SUPPLY – CONTACT US


And a little background why we love muscadines…

Why are Muscadines Special?

  • 40 times the antioxidant power of table grapes
  • 6 times the resveratrol of table grapes
  • The only grape with ellagic acid and ellagitannins
  • Abundant levels of flavonoids, including quercetin

Few traditional fruits are a staple to local culture like muscadine grapes are in the American South.

First cultivated and consumed by Native Americans for hundreds of years, muscadines (Vitis rotundifolia Michx.) go by many names originating from the first tribes, including scuppernongs, bullets, or bullises.  Muscadine is also known in various parts as bull grape, bullet grape, or Southern fox grape.

Muscadine Grape Ingredients

Muscadine grape ingredients work for supplements, foods and beverages, with the resveratrol of 22 glasses of wine.

Muscadines are highly researched and widely consumed in the U.S. More than 100 preclinical and clinical studies have been published on muscadines! And, thousands more studies have evaluated the potential health benefits of the antioxidant molecules found in muscadine.

Muscadine nutrients are in food-bound form, which means they’re bioavailable and better absorbed into cells. And studies show muscadines are more effective at quenching free radicals compared to isolated antioxidants like vitamin C and quercetin at quenching free radicals.

In addition to the high content of antioxidants in Muscadine grape products and extracts, compounds in Muscadine also stimulates the body’s own antioxidant protection mechanisms.

Muscadines’ whole-food synergy was confirmed when studies found it may stimulate both types of antioxidant defensesin the body — exogenous and endogenous. (Most antioxidants only support a limited number of antioxidant pathways).

The polyphenol-preparation from Muscadine grape was tested in a blend with chemically pure resveratrol.The blend containing Muscadine polyphenols reduced the inflammatory response to a test meal, in part via the induction of genes involved in production of antioxidant enzymes, called “Antioxidant Response Elements (ARE)”, These include genes, such as Nrf-2, that regulate the expression of antioxidant proteins that protect against oxidative damage triggered by injury and inflammation,

Muscadine grape polyphenols contribute to the regulation of our genes to increase our body’s own antioxidant protection, beyond the antioxidants in the grape itself.

The various health benefits of muscadine have been studied in clinical and preclinical trials. Some of the areas of health areas studied include:

  • Potent Antioxidant; Supports Body’s Antioxidant Defense
  • Energy and Mitochondrial Biogenesis
  • Healthy Aging
  • Cardiovascular Support & Healthy Blood Pressure
  • Men’s Health & Prostate Health
  • Healthy Metabolism
  • Brain and Cognitive Health
  • Sports Nutrition
  • Liver Support, Detoxification
  • Inflammation

​For these reasons, Muscadines, also known as “Super Grapes” are expected to be the ultimate anti-aging food for this century!

Synergy From Multiple Classes of Polyphenols in Muscadines 

Polyphenols from foods are widely studied to support the function of brain, heart, liver, joints, muscle recovery, and other organs. As antioxidants, they support the body’s cellular function and recovery from normal metabolism, and reduce oxidative stress and inflammation associated with many disease states.

Muscadine’s polyphenols are unique because they contain both resveratrol and ellagic acid, two antioxidants that are found in red wine, pomegranate and berries. Resveratrol is a well-researched antioxidant that is shown to extend lifespan in animals, act on mitochondria to improve metabolic function, and possess a number of beneficial activities when consumed.  Ellagic acid and gallic acid, plus the polyphenolic tannins from which they are derived during ripening and processing, are potent antioxidants that have diverse metabolic and inflammation-mediating activities.

Muscadine also contains flavonoids such as anthocyanins and quercetin, which lend a purple-red or yellow hue to the fruit, respectively.  Catechin flavonoids such as epicatechin, epicatechin gallate, and proanthocyanidin tannins are also found in the fruit, mainly in the seed.

Primary muscadine polyphenols include:

  1. Resveratrol, a well-researched antioxidant that is shown to extend lifespan in animals, acts on mitochondria to improve metabolic function, and possess a number of beneficial activities when consumed.
  2. Ellagitannins, including ellagic acid and gallic acid, are potent antioxidants that have metabolic, anti-inflammatory and anti-cancer activities.
  3. Muscadine also contains flavonoids such as anthocyanins and quercetin, which lend a purple-red or yellow hue to the fruit, respectively.
  4. Catechin flavonoids such as epicatechin, epicatechin gallate, and oligomeric proanthocyanidin tannins are also found in the fruit, mainly in the seed.

Muscadines are very high in antioxidant capacity relative to other antioxidants. This data, along with the limited clinical evidence, supports strong antioxidant claims for muscadine:

Whole Muscadine Fruit Extract – 23,000
Muscadine Seed Extract – 17,000
Grape Seed Extract (Conventional) – 11,000
Whole Muscadine  Fruit Powder – 3,000
Muscadine Fruit Skin – 5,000
Muscadine Seed – 4,000
Muscadine Juice Concentrate – 4,000
Acai powder – 1027
Bilberry, dried – 500
Elderberry – 150
Cranberry – 90
Plums – 85
Blueberry juice – 24
Concord grape juice – 24
Grape juice, red – 18
Grapes – fresh black – 17
Grapes – fresh red – 18
Green tea, brewed – 13

Reference: Total ORAC Data from USDA ORAC Database (2010). The cited 2010 data for Total ORAC was separated into 2 assays: hydrophilic and lipophilic. Muscadine ORAC data is the sum of six ORAC subtests. 

 

Algal DHA (Omega-3) -- 40-50% DHA (Canada)
$90/kg+
Algal DHA (Omega-3) -- 40-50% DHA (Canada) Image

Algal DHA (Omega-3) — 40-50% DHA (Canada)

Algal oil DHA Omega-3

Algal oil DHA Omega-3 are becoming a preferred source for Omega-3 fatty acids

With increasing demand placed upon global fisheries, and an ever-growing population, we can’t continue to rely solely on the sea to meet omega-3 needs. 

However, most plant-based omega-3s only offer short-chain alpha-linolenic acid, a less active form of omega-3s that are inefficiently converted by the body into biologically relevant EPA and DHA. This conversion process is inefficient, and often rendered ineffective by essential fat imbalances which typify the Western diet, such as high omega-6 intake. 

Fish happen to excel at this conversion, but so do certain strains of algae – the original source of omega-3s.

 

Key Attributes

• Non-GMO algal oil

• Vegan/Vegetarian

• Allergen free

• Clean and clear label

Algae Omega-3 DHA EPA

Algae Omega-3 contains predominantly DHA with smaller amounts of EPA

Freshness

If you’ve ever tasted the dreaded fish burp, you’ve tasted oxidized fish oil. The omega-3 DHA molecule is uniquely sensitive to air due its many double-bonds. Optimizing freshness and shelf stability requires processing expertise. Patented processing means that these delicate chains of fat are protected from oxidation – which means a better taste in your mouth.

Mouthfeel

Slick, slimy algae? Not so much. With a diverse variety of delivery options, a range of omega-3 offerings are available in delightfully subtle forms.

Taste

Algal oil undergoes an environmentally-friendly, chemical-free extraction process to eliminate virtually all traces of taste and odor – making the a tasteless omega-3 oil an ideal ingredient in foods and beverages where manufacturers want the nutritional benefits of plant-derived omega-3 DHA without a fishy smell or taste.

Quality by Design in Omega-3’s

Whereas ocean-sourced omega-3s have to undergo many purification processes to remove the environmental contaminants ubiquitous in seawater, improved sources  never expose the algae to contaminants in the first place, with a proprietary omega-3 processing protects the oil from environmental contaminants or pollutants.

Uses a patented solvent-free process to extract omega-3 EPA and DHA, using food-grade enzymes to harvest omega-3 EPA and DHA. No solvents, petroleum distillates, hexanes 

Produced with a fermentation process similar to beer or kombucha making, in a closed environment specially created to maximize omega-3 output. 

APPLICATIONS

  • Tablets and Capsules
  • Gel caps & capsules
  • Gummies
  • Soft chews
  • Supplement beverages

 

Delivery Methods

Standard algal DHA oil can be widely found in infant formula, prenatal and dietary supplement applications.  Improved delivery choices are available that overcome pill fatigue with a range of offerings such as: 

  • Emulsified oils with a creamy, non-oily texture 
  • Tasteless, odorless, shelf-stable oils
  • Heat-stable powders

Sustainability

Microalgae produce nutrition using renewable inputs — water and sunlight.  A number of studies have evaluated the potential for algal byproducts as sustainable nutrition sources. Omega-3 fatty acids EPA and DHA are found in animals, transgenic plants, fungi and many microorganisms but are typically extracted from fatty fish, putting additional pressures on global fish stocks. 

Several heterotrophic microalgae have been used as biofactories for omega-3 fatty acids commercially, but a strong interest in autotrophic microalgae has emerged in recent years as microalgae are being developed as biofuel crops. 

 

Algal DHA Omega-3 from Algae

Algal DHA Omega-3 Sustainability Cycle

Source: https://www.sciencedirect.com/science/article/pii/S0048969718338750

 

Astaxanthin (Algae) - 5-20% Standardized Extract, Natural Source
$320/kg+
Astaxanthin (Algae) - 5-20% Standardized Extract, Natural Source Image

Astaxanthin is a naturally occurring dark red carotenoid found in nature primarily in aquatic animals such as salmon, trout, krill, shrimp, crayfish, and crustaceans. The microalgae Haematococcus pluvialis which grows in fresh water throughout the world is the richest natural source of astaxanthin. Humans, unlike crustaceans, cannot synthesize astaxanthin and have to acquire it through their diet.

Astaxanthin Algae Antioxidant

Astaxanthin is a potent antioxidant from algae.

Astaxanthin however, is more than just a red pigment, it is one of the most powerful lipophilic antioxidants yet discovered. It has the unique capacity to quench free radicals and reactive species of oxygen and to inhibit lipid peroxidation. Studies have shown natural astaxanthin to be over 500 times stronger than vitamin E and much more potent than other carotenoids such as lutein, lycopene and beta-carotene. Moreover, astaxanthin, a xanthophyll carotenoid, is a nutrient with a unique molecule structure; it does not convert to vitamin A (retinol) and has no “pro-oxidant” activity.

Numerous studies from around the world have established the use of natural astaxanthin produced from Haematococcus pluvialis microalgae as a potent antioxidant with proven beneficial effects for human health.

Astaxanthin was shown to decrease the risks of certain chronic diseases related to oxidative stress, supports healthy cardiovascular activity, improves muscle strength and endurance, prevents premature skin aging and joint health. Additionally, astaxanthin protects the body under stress conditions and has anti-inflammatory and immune-stimulating effects. Astaxanthin has been shown to actually cross the blood-brain and blood-retinal barriers, meaning it can positively impact disorders related to eye, brain and central nervous system, among others.

Why Natural over Synthetic?

Haematococcus pluvialis is the organism that naturally produces the highest concentrations of astaxanthin. This green microalga is found in freshwater pools around the world. The conditions in these pools can change very rapidly. As the pool begins to dry up, levels of nutrients drop and UV radiation from the sun increases.

In response to these changes, H. pluvialis begins to produce astaxanthin. In fact, it produces so much astaxanthin that the entire cell of the algae turns bright red. The astaxanthin’s powerful antioxidant capacity protects the algae’s delicate cellular machinery, allowing the algae to survive in very harsh conditions. Even if the water in the pool dries completely, the astaxanthin allows the algae to survive for months or even years. In other words, natural evolution has made H. pluvialis an ideal source of astaxanthin.

However, cultivating H. pluvialis to produce natural astaxanthin in the quantities needed for use in nutraceutical supplements and functional foods is a challenging and extremely technical process.

Astaxanthin Fish Seafood Antioxidant

Astaxanthin is an antioxidant found in fish and seafood

As an increasing number of clinical studies have shown the health benefits of natural algae astaxanthin and its popularity has increased, some have tried to take a short cut by introducing synthetic versions of astaxanthin for use in human supplements. These synthetic versions of astaxanthin are sometimes labeled as “nature identical” or “nature equivalent.”  However, there are many important molecular differences between natural algae astaxanthin and artificial versions produced by chemical synthesis from petrochemicals.

Despite being described as “nature identical,” synthetic astaxanthin is clearly different from natural algae astaxanthin in important ways. Natural algae astaxanthin is more than 95% esterified. This means natural fatty acids are attached to one or both ends of the molecule. By contrast, synthetic astaxanthin is all free form, or unesterified.

Astaxanthin Natural vs Synthetic

Astaxanthin in natural form may have different activity than in synthetic form.

Beyond the striking biochemical differences between algal and synthetic astaxanthin, data demonstrates clearly that algal astaxanthin is 10X as bioavailable as synthetic.  This is critical information when one considers how important  bioavailability is to achieving the benefits of any dietary supplement.

PRODUCT ATTRIBUTES

NaturPro has evaluated and certified two high-quality suppliers of natural algal-sourced astaxanthin.  These suppliers offer a wide range of form factors for use in food, dietary supplements and pet supplement applications.

Available form factors include:

  • 5% astaxanthin extract oleoresin
  • 10% astaxanthin extract oleoresin
  • 20% astaxanthin extract oleoresin
  • 2% astaxanthin extract powder (cold-water dispersible)
  • 2% astaxanthin extract powder (cold-water soluble)
  • 5% astaxanthin vegetarian beadlets
  • 1% water soluble astaxanthin extract
  • 4 mg softgels in bulk
  • 12 mg softgels in bulk
  • Whole algae powder
  • 4 mg astaxanthin whole algae tablets in bulkThe whole algae comprises the complete array of powerful naturally-occurring constituents not found in extracted astaxanthin, including astaxanthin and other antioxidants, polysaccharides and dietary fibers, essential fatty acids and vitamins & minerals.

Note:  many of the products above are available in organic as well as conventional status

Antioxidant Properties

As an Antioxidant, Astaxanthin is:

  • 110 times stronger than Vitamin E
  • 560 times stronger than Green Tea catechins
  • 800 times stronger than CoQ10
  • 3000 times stronger than Resveratrol
  • 6000 times stronger than Vitamin C

Safety

Astaxanthin has been in the human diet for at least as long as we have consumed seafood.  It is found in seafood such as shrimp and crabs, and fish like salmon and trout, large quantities of which are consumed by people all over the world.  For perspective, a normal-sized sockeye salmon stake typically contains between 4 and 6 milligrams of astaxanthin, and dietary supplement dosages of 4 mg have been sold since the 1990s – millions and millions of doses with no adverse reactions reported.

Additionally, there have been hundreds of studies performed using dosages of up to 20 mg/day of astaxanthin, with no reported adverse effects. Some work has been done using acute dosages of 40 mg/day which was said to have been “well-tolerated” by the subjects; however, incidence of dosages that high in the body of astaxanthin science has been infrequent.

APPLICATIONS

Because of astaxanthin’s tremendous benefits across multiple categories of human health, manufacturers have designed numerous form factors to enable consumers the widest possible access to astaxanthin.  Among these are:

  • Dietary Supplement Applications
    • Softgel Capsules
    • Two-Piece Capsules
    • Tablets
    • Instant Drink Powders
    • Nutritional Bars
    • Liquid Shots
    • Ready-to-Drink Beverages
    • Sachets
    • Gummies
    • Soft Chews
  • Personal Care Applications
    • Topical Creams
    • Topical Emulsions
  • Food and Beverage Applications
    • Yogurt
    • Nutritional Bars
    • Chocolate Confections
    • Beverages
      • Coffee
      • Tea
      • Milk Products
      • Water Beverages
    • Baked Goods
    • Cereals
    • Chewing Gum
    • Dairy Product Analogs
    • Frozen Dairy Desserts and Mixes
    • Hard Candy
    • Soft Candy
    • Processed Fruits and Fruit Juices
    • Processed Vegetables and Vegetable Juices
    • Pet Supplements

 

BENEFITS

In recent years, astaxanthin has been among the most widely-researched dietary supplements because of its incredibly potent antioxidant properties.  Recent and ongoing studies number in the hundreds, and new, exciting results attesting to its benefits are announced on a regular basis.  Areas that continue to be investigated include (but are not limited to) the following:

  • Antioxidant Activity of Astaxanthin
  • Anti-Inflammatory Properties of Astaxanthin
  • Astaxanthin and Eye Health
  • Anti-Atherosclerotic Properties of Astaxanthin
  • Photoprotective Properties of Astaxanthin
  • Immunomodulating Properties of Astaxanthin
  • Astaxanthin and Cardiovascular Health
  • Astaxanthin and Neurodegenerative Diseases
  • Astaxanthin and Heat Stress
  • Anti-Fatiguing Effects of Astaxanthin
  • Anticancer Activity of Astaxanthin
  • Astaxanthin and Male Fertility
  • Lipid Profile Improvement from Astaxanthin
  • Endurance-Boosting Effects of Astaxanthin
  • Cosmetic Benefits of Astaxanthin
  • Safety and Bioavailability of Astaxanthin
  • Superiority of Algal-based Astaxanthin over Synthetic

As discussed, NaturPro has evaluated and certified two superior-quality astaxanthin manufacturers, who have expended considerable resources performing clinical and scientific studies as to the benefits of natural astaxanthin.  Among the clinically-supported benefits for astaxanthin supplied by these specific manufacturers are:

  • Muscle Performance
    • Boost muscle endurance and recovery
    • Lowers lactic acid and fatigue
    • Improves muscle fatigue that may lead to sports performance benefits
    • Reduces muscle damage and inflammation (that may occur from over-exertion during strenuous exercise)
    • Reduces muscle damage, oxidative stress and improves antioxidant response
    • Improves fitness, strength/endurance and strength/explosivity
    • Significantly improved TT (cycling time trial) performance
    • Improves blood flow and the quality of red blood cells
    • Enhances fat metabolism by improving mitochondria function
  • Eye Health & Vision
    • Improving eye fatigue, eye irritation & blurred vision linked to computer and digital device use
    • Improving capillary blood flow
    • Improves visual acuity
    • Reducing inflammation of the ciliary muscle (that may occur with excessive computer and digital device use)
  • Skin Health
    • Revitalizes photoaged skin by quenching oxidative stress in all skin layers
    • Reduces the size of wrinkles and improves skin microtexture
    • Improves elasticity in the skin by strengthening the collagen layer
  • Immune Health
    • Faster immune response
    • Strengthens and balances the immune system
    • Enhances antibody production
    • Protects immune cells against oxidative stress
  • Heat Stress
    • Effective in treating and preventing heat stress induced by factors such as high temperatures or strenuous physical activities

Other benefits that have been demonstrated in the general literature on algal-sourced astaxanthin include:

 

  • Skin Health
    • Increases the amount of time before the skin starts to burn
    • Improves elasticity and moisture
  • Joint & Tendon Health
    • Increases grip strength
    • Helps reduce discomfort from carpal tunnel syndrome
  • Eye & Brain Health
    • Astaxanthin can cross the blood-retinal barrier
    • Protects eyes from light-induced damage
    • Reduces eye strain and fatigue
    • Lessens oxidative stress on the brain
  • Cardiovascular Health
    • Supports healthy blood flow
    • Helps keep CRP and blood lipid levels at normal range
    • Improves HDL-C

 

SUSTAINABILITY

As both manufacturers verified by NaturPro grow their algae in enclosed photobioreactor systems, there is no impact on natural availability of this algae; in addition, no harsh chemicals are used in the extraction process.

Both manufacturers have achieved Non-GMO Project Verified status.

 

 

Mint -- Peppermint, Spearmint -- Single Estate (US Pacific Northwest)
$24/kg+
Mint -- Peppermint, Spearmint -- Single Estate (US Pacific Northwest) Image

NaturPro Verified Mint is sourced from  the largest mint producing area in the Pacific Northwest.

Our farms grow single-cut, premium-quality heirloom Black Mitcham Peppermint and Native Spearmint.

The mint they raise is sustainably harvested and has a unique flavor that cannot be found anywhere else. The way they grow their mint, the region’s climate, the rich soils and their harvesting methods make their mint extraordinarily smooth and refreshing.

The essential mint oils are steam distilled only once to retain the full flavor spectrum and bouquet of real Pacific Northwest mint.

Not much has changed over the years when it comes to the way we grow and harvest mint, although some of the more labor-intensive steps are now mechanized.

Our farms focus on quality instead of quantity, taking only one harvest off the mint each year. This philosophy means less dependence on commercial agronomic products and more reliance on the natural physiology of the plant and the seasons.

Elderberry Extracts and Concentrates (European)
$320/kg+
Elderberry Extracts and Concentrates (European) Image

Black Elderberry (Sambucus nigris) is widely known as a potent source of antioxidants and for its immune supporting properties.

NaturPro has qualified a line of high-quality elderberry extract products manufactured using Austrian black elderberries (Sambucus nigra, L.) of the variety “Haschberg.

This line delivers standardized amounts of anthocyanins in liquid or powdered format, and was developed using a chemical-free process which enriches active compounds including polyphenols.

Verified elderberry extracts and concentrates for immune support

Verified elderberry extracts and concentrates for immune support

Phytonutrient Profile

  • Contains nearly four times the anthocyanins as other commonly consumed berries
  • Unique anthocyanin profile containing cyanidin-3-glucoside, cyanidin-3,5-diglucoside, cyanidin-3-sambubioside, cyanidin- 3-sambubioside-5-glucoside
  • Rich in flavonoids like isoquercetin and catechins

Elderberry Benefits

  • Supports a healthy immune system
  • Promotes enhanced athletic performance
  • Promotes a healthy cardiovascular system
  • Promotes healthy aging and inflammation responses

Product Applications

Elderberry liquids and powders are ideal for a variety of applications including functional foods and beverages, dietary supplements, and as natural colorants. They are suitable for use in capsules, tablets, drink mixes, cosmetics, and more.

Elderberry standardized extract ingredients

Elderberry standardized extract ingredients provide clinically studied dosages of anthocyanins, flavonoids and polyphenols

Elderberry Juice Concentrate (65° Brix: organic) 

Pure Elderberry (Sambucus nigra) juice concentrate.

Juice Powder 5:1 (spray-dried concentrate, non-standardized, conventional & organic) 

Pink-purple powder perfect for enhancing products naturally.

3.2% Liquid* (conventional & organic) 

European black elderberry liquid standardized to a minimum anthocyanin content of 3.2%.

7% Powder* (conventional & organic) 

Spray-dried European black elderberry extract standardized to a minimum anthocyanin content of 7%.

14% Powder* (conventional & organic) 

Spray-dried European black elderberry extract standardized to a minimum anthocyanin content of 14%.

Health Benefits

  • Bioavailability
  • Immune Support
  • Stress and Performance
  • Antioxidant and Cardiovascular Support

Elderberry has been extensively studied for bioavailability. In one particular human study by Cao et al. (2001), elderly women consumed an acute dosage of standardized elderberry extract, and anthocyanins were detected as glycosides in both plasma and urine. Further analysis of the urine by HPLC-MS/MS confirmed the existence of two main anthocyanins in elderberry (cyanidin-3-glucoside and cyanidin-3-sambubioside) as well as four metabolites. Other studies by Milbury and his team (2002) confirmed the absorption of anthocyanins in their glycosylated forms and identified various metabolized forms. Wu et al. (2002) discussed the fact that absorption from an extract will likely be better than from the raw plant where the anthocyanins have not been extracted from the plant cell.

All elderberry products are also available in NOP certified organic upon request.

 

Matcha Green Tea (Japan)
$45/kg+
Matcha Green Tea (Japan) Image

NaturPro has verified one of the oldest manufacturers of  matcha tea (Camellia sinensis) for world class tea products.

The most authentic, high quality matcha, with the highest safety standards in the industry, comes from experience.

Our matcha suppliers are comprised of highly skilled professionals who intimately understand the complexity of tea.

Supported by Organic and GMP certifications, all materials must pass strict quality control and taste testing by trained tea sommeliers.

A wide-range of customers, from major world class companies to boutique tea shops are primary clients for this ultra-premium source of matcha.

Japanese Matcha Green tea cake, tea and cake

Japanese Matcha Green tea can go into almost any food and beverage

Ceremonial Grade Matcha

Ceremonial grade matcha green tea is some of the finest green tea in the world and a very healthy way to consume matcha green tea. Primarily associated with the Japanese Tea Ceremony or Chanoyu, ceremonial matcha grade green tea has been consumed for hundreds of years because of it’s great taste and numerous health benefits.

Ceremonial matcha is grown in Japan in the Aichi prefecture. Prior to the harvest of matcha, the tea plants are shaded to bring out brightness and sweetness not associated with other green teas. The leaves are then harvested and processed, and ceremonial matcha tea is ground down to powder.

Today, matcha is still used in the Japanese Tea Ceremony, but also in a variety of other manners. Ceremonial matcha is used in cakes, pies and ice cream, as an ingredient in baked goods and entrees and it is especially popular in lattes and smoothies.

When it comes to choosing certified Organic matcha, it will all boil down to the taste.  Organic matcha has a fresh, umami flavor with crisp, bold accents that have your taste buds asking for more.

The tea leaves are harvested from the field, steamed, and manufactured as quickly as possible after harvest to preserve the aroma and taste.

Organic matcha green tea contains all the same great health benefits and antioxidants as normal matcha, while also providing a steady boost of energy with no crash making it perfect in the morning, as an afternoon pick-me-up of to settle in after dinner.

Organic Matcha green tea

Organic Matcha green tea is a stimulating, grassy umami delight

HISTORY OF MATCHA

The history of matcha green tea dates back several centuries. In 1271, tea cultivation began in Nishio, Japan, by the priest Shoichi, founder of the temple of Jissoji. Shoichi’s temple was in constant competition with the neighboring temple of Shonenji over rights to the nearby tea plants. For more than 400 years, these two temples battled for ownership until in 1692, a judgment awarded the coveted plants to Jissoji.

Nearly two hundred years later, after the Meiji Restoration of 1868, matcha production was finally embraced in Nishio. The chief priest of a nearby Buddhist monastery named Jundo Adachi introduced a new variety of tea and production techniques from Uji, which was a major production center of dried green tea powder.

Turmeric Extract (India)
$160/kg+
Turmeric Extract (India) Image

Numerous benefits have been derived from the colorful and aromatic qualities of the Indian spice.

Curcuminoids are responsible for the rhizome’s yellow-orange color, while an array of essential oils host the flavorful aroma at the heart of traditional curries.

Long usage in traditional Ayurvedic and Chinese medical healing systems, turmeric has been repeatedly validated by the scientific data of today.

NaturPro has verified a product of a unique extraction process that combines curcuminoids and essential oils, including aromatic turmerone.

Olive Leaf Extract - Oleuropein 20-40% (Europe)
$
Olive Leaf Extract - Oleuropein 20-40% (Europe) Image

Olive Leaf Extract – Oleuropein (Europe)

Since ancient times, people have used the oil and eaten olives, especially in Mediterranean cuisine. Historically, olive leaves were used to treat fevers, and for the topical treatment of wounds or infections. Its leaves have served as remedies since the age of the Ancient Greeks, who used them to combat high blood pressure and diabetes.

In Yemen, people used to eat and chew olive leaves, and it is reported that Yemenites never suffered from diabetes. Olive leaf tea is commercially available in Europe, and is recommended in at least one traditional medicinal encyclopedia for use in the case of high blood pressure. Olive leaves are also used as a spice, and are classified as flavorings in a Council of Europe publication.

Olive leaf extract heart health

Olive leaf extract is studied for heart and cardiovascular health

Ever since it was discovered that the incidence of heart attack is much lower across the Mediterranean than in other areas of the world, the positive effects of a Mediterranean diet have been widely discussed. At the center of these discussions has always been olive oil. Its unsaturated fatty acids and antioxidant ingredients, such as the polyphenol Oleuropein, provide protection against cardiovascular disease, and other heart benefits. What most people don’t realize is that this health-promoting substance is found not only in the olive fruit, but actually in higher concentrations in the leaves of the olive tree (Olea europaea L.).

Oleuropein is rapidly degraded by colonic microflora, producing one of its most important metabolites, Hydroxytyrosol (HT). HT is also found in the olive leaf and olive oil, and is thought to be among the most potent antioxidants found in nature.  Based on detailed investigations, it is suggested that HT acts as a scavenger of reactive free radicals leading to neuroprotective effects on neural cells during oxidative stress.

Olive Leaf Extract Ingredient Antioxidant

Olive Leaf Extract is an ingredient providing antioxidants

PRODUCT ATTRIBUTES

Although there are numerous manufacturers in the dietary supplement industry offering olive leaf extracts standardized to various concentrations of Oleuropein, we have identified and evaluated two different ingredients that meet our standards to be called NaturPro Verified Supply™ .  Each of these extracts has been clinically proven to be effective for different benefits, focusing on cardiovascular health in one case, and bone health in the other.

Oleuropein 20%

  • This is a unique ingredient standardized to contain just the right types of polyphenolic compounds, and in just the right proportions, to support cardiovascular health.
  • It is a highly powerful antioxidant that protects blood vessels against the cellular damage caused by free radicals, and is also clinically proven safe and effective.
  • Product purity is assured through a patented extraction process specifically designed to eliminate environmental and other contaminants.
  • The manufacturer suggests dozens of structure-function claims (subject to FDA enforcement action), including
    • Supports blood pressure health
    • Supports normal cholesterol metabolism
    • Supports healthy arterial function
    • Supports normal glucose metabolism

Oleuropein 40%

  • Proprietary olive polyphenol complex with standardized composition
  • Patent protected
  • Strong science and clinically tested
  • Unique positioning as bone health product (stimulates bone formation)
  • Positive consumer awareness of olive antioxidants
  • Low daily dose
  • Safe history of use
  • EFSA claim for anti-oxidant activity

APPLICATIONS

Both ingredients are highly soluble, free-flowing powders, and are suitable for use in capsules, tablets, powdered drink mixes, RTD drinks, and other applications.

BENEFITS

In general, olive leaf extract is a natural source of wellness with therapeutic properties that are:

  • gastroprotective (protects digestive system)
  • neuroprotective (protects central nervous system)
  • antimicrobial (inhibits microorganism growth)
  • anticancer (reduces risk of cancer)
  • anti-inflammatory (reduces risk of inflammation)
  • antinociceptive (reduces pain stimuli)
  • antioxidant (prevents oxidation or cell damage)

Olive leaf extract oleuropein

Olive leaf extract containing oleuropein is clinically studied for cardio and bone health

According to WebMD, “Olive leaf is used for treating viral, bacterial, and other infections including influenza, swine flu, the common cold, meningitis, Epstein-Barr Virus (EBV), encephalitis, herpes, shingles, HIV/ARC/AIDS, and hepatitis B. Olive leaf is also used for pneumonia; chronic fatigue: tuberculosis (TB); gonorrhea; fever; malaria; dengue; ‘blood poisoning’ (bacterial infections in the bloodstream); severe diarrhea; and infections in the teeth, ears, and urinary tract, and infections following surgery. Other uses include high blood pressure, osteoarthritis, osteoporosis, diabetes, hay fever, improving kidney and digestive function, and increasing urine flow.”  This clearly is supportive of the historical evidence of the value of this extraordinary plant.

As discussed above, however, NaturPro has selected two very unique, proprietary extracts with significant clinical evidence of very specific health benefits.  Following is a summary of these benefits.

Oleuropein 20% – Clinically Supported for Cardiovascular Health

  • Clinically-proven Benefits
  • Proved similar to standard hypertensive therapy its ability to decrease blood pressure.
  • Lowered blood pressure and LDL-cholesterol in adults with borderline hypertension.
  • Suggested Mechanisms of Action
  • Promotion of production of nitric oxide (NO), an important mediator of vasodilation in blood vessels. In turn, NO helps relax the smooth muscles surrounding blood vessels, decreasing blood pressure.
  • By binding to angiotensin converting enzyme (ACE), phenolic substances inhibit its action, ultimately decreasing the formation of angiotensin II. This leads to a systematic dilation of arteries and veins, and that decreases arterial blood pressure.

 

Oleuropein 40% – Clinically Supported for Bone Health

Bone metabolism (or bone remodeling) is a lifelong process where mature bone tissue is removed from the skeleton by osteoclasts (a process called bone resorption) and new bone tissue is formed by osteoblasts (a process called ossification or new bone formation). These processes also control the reshaping or replacement of bone following injuries like fractures but also micro-damage, which occurs during normal activity.

In the first year of life, almost 100% of the skeleton is replaced. In adults remodeling proceeds at about 10% per year. As long as the bone-forming activity (absorption) is greater than the bone- breakdown (resorption), adults are able to maintain healthy bones. Many living cells present in bone originate from the same “mother cell”.  These bone stem cells differentiate into different cell types: Osteoblasts (bone building cells), but also adipocytes (fat cells) or other cell types. Due to stress, inflammation and ageing this differentiation shifts to the production of more fat cells and fewer osteoblasts resulting in more fragile and fatty bones.

  • At the cellular level, Oleuropein promotes bone formation by inhibiting adipocyte differentiation, and enhancing differentiation into osteoblasts.
  • A randomized, double-blind, placebo-controlled study proved that this product has significant effects on stimulation of bone building cells (osteoblasts) and blood lipid profiles.
  • Furthermore, results of a pharmacokinetic study show the intake of this ingredient leads to an excellent bioavailability of bioactive metabolites in the target population.

The figure below illustrates the relative mean change in osteoblast activity levels (bone formation marker osteocalcin) per subject over 12 months. The treatment group showed a 32% increase, which was statistically significant.

Olive Leaf Extract Bone Health

Olive Leaf Extract is studied to support bone health

SUSTAINABILITY

Olive tree leaf, a waste by-product of the olive oil industry, is an inexpensive and abundant source of polyphenols of great interest for various applications in the dietary supplement, cosmetic, and pharmaceutical industries. As such, there are no known concerns as to the sustainability of this ingredient.

 

 

 

Muscadine Grape Extracts and Concentrates (Southeast USA) Image
Muscadine Grape Extracts and Concentrates (Southeast USA)
HARVEST SUPPLY AVAILABLE: Sweet, tart and astringent all at once 10-20x more resveratrol than red wine Single source, US grown Full-Spectrum Antioxidant Ingredients: Ultra-premium muscadin... Read More
$90/kg+
Ingredients
Muscadine Grape Extracts and Concentrates (Southeast USA) Image
Muscadine Grape Extracts and Concentrates (Southeast USA)
HARVEST SUPPLY AVAILABLE: Sweet, tart and astringent all at once 10-20x more resveratrol than red wine Single source, US grown Full-Spectrum Antioxidant Ingredients: Ultra-premium muscadin... Read More
$90/kg+
Algal DHA (Omega-3) -- 40-50% DHA (Canada) Image
Algal DHA (Omega-3) -- 40-50% DHA (Canada)
Algal DHA (Omega-3) — 40-50% DHA (Canada) ... Read More
$90/kg+
Astaxanthin (Algae) - 5-20% Standardized Extract, Natural Source Image
Astaxanthin (Algae) - 5-20% Standardized Extract, Natural Source
Astaxanthin is a naturally occurring dark red carotenoid found in nature primarily in aquatic animals such as salmon, trout, krill, shrimp, crayfish, and crustaceans. The microalgae Haematococcus pluvialis which grows in fresh w... Read More
$320/kg+
Mint -- Peppermint, Spearmint -- Single Estate (US Pacific Northwest) Image
Mint -- Peppermint, Spearmint -- Single Estate (US Pacific Northwest)
NaturPro Verified Mint is sourced from  the largest mint producing area in the Pacific Northwest. Our farms grow single-cut, premium-quality heirloom Black Mitcham Peppermint and Native Spearmint. The mint they raise is su... Read More
$24/kg+
Elderberry Extracts and Concentrates (European) Image
Elderberry Extracts and Concentrates (European)
Black Elderberry (Sambucus nigris) is widely known as a potent source of antioxidants and for its immune supporting properties. NaturPro has qualified a line of high-quali... Read More
$320/kg+
Matcha Green Tea (Japan) Image
Matcha Green Tea (Japan)
NaturPro has verified one of the oldest manufacturers of  matcha tea (Camellia sinensis) for world class tea products. The most authentic, high quality matcha, wi... Read More
$45/kg+
Turmeric Extract (India) Image
Turmeric Extract (India)
Numerous benefits have been derived from the colorful and aromatic qualities of the Indian spice. Curcuminoids are responsible for the rhizome’s yellow-orange color, while an array of essential oils host the flavorful aroma at t... Read More
$160/kg+
Olive Leaf Extract - Oleuropein 20-40% (Europe) Image
Olive Leaf Extract - Oleuropein 20-40% (Europe)
Olive Leaf Extract – Oleuropein (Europe) Since ancient times, people have used the oil and eaten olives, especially in Mediterranean cuisine. Historically, olive leaves were used to treat fevers, and for the topical treatment ... Read More