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NaturPro Scientific – Natural Products Consultants

About Us

NaturPro Scientific was founded on a mission to answer numerous challenges and opportunities facing the natural products industry.

We are a boutique natural products consulting firm scientific expertise, analysis and solutions that add value to healthy products that are better for consumers and better for the planet.  

NaturPro has spent years helping to support innovation pipelines, develop industry standards, conduct research trials, develop groundbreaking new products, and support compliance programs for a broad spectrum of clients in the supplement and food industries.

Some of our clients include startups, Fortune-50, mass market, as well as companies large and small, across a number of product formats and applications.

Part of the NaturPro advantage includes access to our team of experts, including some of the top legal, scientific, marketing and business minds in natural products.

We look forward to helping you on your journey!

Blake Ebersole
President
NaturPro Scientific, LLC
blake@npscientific.com


Professional Profile:

Blake Ebersole, B.S., M.B.A., founder and President of NaturPro Scientific LLC, is an expert in the innovation, development and production of natural products supporting human health for foods, drugs and dietary supplements. Trained in chemistry, Blake has worked from seed to shelf on numerous projects to add lasting value to healthy consumer products, ingredients and raw materials. Blake has been integral in the development of a number of successful products and ingredients supporting human health, leading to several patents and more than 70 peer-reviewed publications. 

In regulatory and quality assurance roles, Blake has spearheaded a number of compliance and quality management programs based on FDA, HACCP, GMP, GLP, GACP and ISO standards that govern regulated natural products industries around the globe. Blake is a contributing writer to industry trade and educational publications, and participates on standards-setting committees such as ASTM International, AOAC International and the American Herbal Products Association. 

Curriculum Vitae


About NaturPro:

NaturPro Scientific, LLC, is a boutique natural products scientific consulting firm offering more than 30 years of experience and solutions supporting the development of innovative and functional products and ingredients that promote human health. NaturPro provides essential seed-to-shelf guidance covering innovation, research, production, supplier verification, quality assurance and regulatory compliance. NaturPro supports a range of startups, midsize and Fortune-50 corporations in the dietary supplement, food and beverage, and other regulated industries. 


We Are Active Members of:


--American Botanical Council
--American Herbal Products Association (Standards, Raw Materials, Laboratory and Cannabis Committees)
--AOAC International (Ethanol in Kombucha Expert Panel)
--ASTM International (D.037 Cannabis Committee)
--International Society of Sports Nutrition
--U.S. Hemp Roundtable (Technical Committee)


Recent Scientific Publications:

    1. Determination of Ethanol Content in Kombucha Products by Gas Chromatography with Flame Ionization Detection: A Multilaboratory Study. Liu Y, Chan M, Ebersole B, Sy H, Brown PN. J AOAC Int. 2018 Sep 18. doi: 10.5740/jaoacint.18-0190.

    2. Historical Food and Supplement Adulterant List, Ebersole B. 2017, Self-published. Source: http://naturproscientific.com/historical-food-and-supplement-adulterant-list/ 

    3. Curcumin Has Mixed Effects on Oxidative Stress in Patients with Nonmetastatic Prostate Cancer following Radiation Therapy, Ebersole B.  HerbClips™, American Botanical Council, September 2017

    4. Aromatherapy Using Lavender Oil or Linalyl Acetate Modestly Improves Pain Relief in Patients with Colorectal Cancer following Post-surgery Catheter Removal, Ebersole B.  HerbClips™, American Botanical Council, September 2017

    5. Loquat Leaf Extract without Additional Exercise Does Not Increase Muscle Mass in Healthy Adults, Ebersole B. HerbClips™, American Botanical Council, August 2017

    6. Meta-analysis Provides Update of Aromatherapy for Depression, Ebersole B.  HerbClips™, American Botanical Council, August 2017

    7. Petitgrain Oil Aromatherapy Reduces Markers of Stress and Modestly Improves Performance in Simulated Workplace Environment, Ebersole B.  HerbClips™, American Botanical Council, August 2017

    8. Bromelain Improves Facial Swelling following Oral Surgery, Ebersole B. HerbClips™, American Botanical Council, July 2017

    9. Single Serving of Montmorency Tart Cherry Concentrate Improves Cerebral Blood Flow, but Not Cognitive Function, Ebersole B. HerbClips™, American Botanical Council, August 2017

    10. Kale Reduces Postprandial Spikes of Plasma Glucose in Healthy Japanese Adults, Ebersole B.  HerbClips™, American Botanical Council, July 2017

    11. A Two-week, Pilot Study on the Reduction of Irritable Bowel Syndrome Symptoms with Atrantíl®, Ebersole B.  HerbClips™, American Botanical Council, July 2017

    12. Hibiscus Water Extract Demonstrates Significant Antioxidant Effects in Patients with Marfan Syndrome, Ebersole B.  HerbClips™, American Botanical Council, June 2017

    13. Weight Reduction with Meratrim® Botanical Extract Combination in Overweight Humans—A Randomized, Controlled Trial, Ebersole B.  HerbClips™, American Botanical Council, June 2017

    14. Standardized Cranberry Extract, Cranpac™, Reduces Bacterial Adhesion in Patients with Recurrent Urinary Tract Infection, Ebersole B.  HerbClips™, American Botanical Council, May 2017

    15. Efficacy of a Fruit and Vegetable Powder Supplement for Menopausal Symptoms in Women, Ebersole B.  HerbClips™, American Botanical Council, May 2017

    16. Efficacy of Coenzyme Q10 and Tea Tree Oil for Chronic Periodontitis, Ebersole B.  HerbClips™, American Botanical Council, May 2017

    17. Standardized Ginger Extract May Reduce Adverse Events from Tuberculosis Drugs, Ebersole B.  HerbClips™, American Botanical Council, April 2017

    18. Review of Contact Dermatitis Associated with Tea Tree Oil Exposure, Ebersole B.  HerbClips™, American Botanical Council, June 2017

    19. Efficacy of a Diet Program on Body Weight in Overweight Americans: Open‐Label Human Study. Ebersole B. March 2017. Technical Report, self-published on client website.

    20. Pilot Studies on the Efficacy of a Diet Program on Body Weight in Overweight and Obese South Africans, Ebersole B. March 2017. Technical Report, self-published on client website.

    21. Analysis of Sugars in Kombucha Tea by High Performance Liquid Chromatography, Ebersole B. Technical Report, October 2016. DOI: 10.13140/RG.2.2.24141.23522

    22. AOAC International First Action Official Method 2016.12, Determination of Ethanol in Kombucha. Ebersole B. 

    23. Single laboratory validation of a GC-FID method for ethanol in kombucha, Ebersole B, Eckert M, Schmidt R, Chan M, Brown P.  2017 Journal of AOAC, doi: 10.5740/jaoacint.16-0404

    24. AOAC Standard Method Performance Requirements 2016.001. Journal of AOAC, (2016) 99(4), 1120-1121

    25. Bitter melon extract attenuating hepatic steatosis may be mediated by FGF21 and AMPK/Sirt1 signaling in mice. Yu Y, Zhang XH, Ebersole B, Ribnicky D, Wang ZQ. Scientific Reports (Nature). 2013 Nov 5;3:3142. doi: 10.1038/srep03142.

    26. Optimization and validation of ursolic acid by HPLC in Ocimum sanctum. Shah J, Patel S, Ebersole B, Hingorani L.  Planta Medica 2012 DOI: 10.1055/s-0032-1321177

    27. Acute human pharmacokinetics of a lipid-dissolved turmeric extract, Shah J, Patel S, Ebersole B, Hingorani L. Planta Medica 2012 DOI: 10.1055/s-0032-1320664

    28. Sustained cognitive effects and safety of HPLC-standardized Bacopa monnieri extract: A randomized, placebo controlled clinical trial. Hingorani L, Patel S, Ebersole B. Planta Medica 2012; DOI: 10.1055/s-0032-1320681

 

Poster Presentations:

      1. Safety, tolerability and nutrient status after consuming a total meal replacement beverage for 30 days: a randomized, controlled pilot study in healthy adults. Ebersole B. International Society for Sports Nutrition Annual Meeting, June 7, 2018.

      2. Single Laboratory Validation of Ethanol in Kombucha by Gas Chromatography with Flame Ionization Detection. Ebersole, B. AOAC International Annual Meeting, September 2016.

      3. Ethanol analysis of kombucha products with gas chromatography. Ebersole B, Institute of Food Technologists Annual Meeting, 2016. 

      4. Acute human pharmacokinetics of a lipid-dissolved turmeric extract. Shah J, Patel S, Ebersole B, Hingorani L.  2012 International Congress on Natural Products Research, New York, NY. July 31, 2012. Planta Med 2012; 78 - PH5 DOI: 10.1055/s-0032-1320664

      5. High-throughput screening program for commercial single-herb extracts. Hingorani L, Seeram NP, Ebersole B.  2012 International Congress on Natural Products Research, New York, NY. July 31, 2012. Planta Med 2012; 78 - PF85 DOI: 10.1055/s-0032-1320632

      6. Optimization and validation of ursolic acid by HPLC in Ocimum sanctum. Hingorani L, Ebersole B, Patel S.  2012 International Congress on Natural Products Research, New York, NY. July 31, 2012. 

      7. Orthogonal validation of analytical and quality systems for botanical products. Hingorani L, Patel S, Darji B, Ebersole B.  2012 International Congress on Natural Products Research, New York, NY. July 31, 2012. Planta Med 2012; 78 - PJ156 DOI: 10.1055/s-0032-1321316

      8. Sustained cognitive effects and safety of HPLC-standardized Bacopa monnieri extract: a randomized, placebo-controlled trial. Hingorani L, Patel S, Ebersole B.  2012 International Congress on Natural Products Research, New York, NY. July 31, 2012. 

      9. Bitter melon extract enhances insulin sensitivity by modulating FGF21 signaling in high-fat diet fed mice. Wang ZQ, Yu Y, Zhang XH,  Li H, Qin J, Ebersole B, Cefalu WT. 7th International Conference for Functional Foods in the Prevention and Management of Metabolic Syndrome,  Southern Methodist University, Dallas, TX, USA, December 3-4, 2010. 

 

Oral Presentations:

      1. “Current Issues for Food Analysis”, Department of Nutrition and Food Science, Texas A&M University, October 25, 2017

      2. “An Overview of the Food and Supplement Regulatory Climate”, Department of Nutrition and Food Science, Texas A&M University, March 16, 2017

      3. “Identity Testing and Method Validation for Botanicals”, Supplyside West, October 5, 2016.

      4. “Emerging Regulatory and Labeling Issues for Dietary Supplements and Foods”, Department of Nutrition and Food Science, Texas A&M University, September 5, 2016.

      5. “Natural Products Research for Neurodegenerative Diseases”, NIH/NINDS, Bethesda, MD, March 3, 2015.

      6. “Longvida: The Brain Curcumin”. Vitafoods International Conference, Geneva, Switzerland, May 24, 2012.

      7. “100% Ingredient Identity”. SupplySide Marketplace Good Manufacturing Practices Workshop, NY, NY, May 8, 2012.

      8. “Nutraceuticals: An Overview”. Department of Nutrition and Food Science, Texas A&M University, April 6, 2012.

      9. “Fortification of Polyphenols into Functional Foods”.  Prepared Foods R&D Applications Seminar, Chicago, IL, USA, August 3, 2011. 

      10. “Science-based Curcumin”, 16th International Food Ingredients and Additives (IFIA) Conference, Tokyo Japan, May 19, 2011.

      11. “Bioavailability of Botanical Supplements: Challenges and Opportunities”.  Department of Nutrition and Food Science, Texas A&M University, March 31, 2011.

      12. “Foods Designed for Health, Functional Foods, and Nutraceuticals”.  Department of Nutrition and Food Science, Texas A&M University, March 20, 2008.

Publications in Non-Academic Press:

    1. Article, “FDA Speaks Truth to DEA: CBD unlikely to be abused”, LinkedIn, October 2018

    2. Article, "Secrets to Ensuring Accuracy from Third Party Testing Labs", LinkedIn, October 2018

    3. Press Release, “Botanical Liaisons and NaturPro Scientific Complete Independent Authentication of Rhodiolife® Rhodiola rosea L. Ingredient”, October 2017

    4. Article, “Emerging Heart Health Ingredients”, Natural Products Insider, August 2017

    5. Article, “Making a Quilt from the Regulatory Patchwork,” Natural Products Insider, July 2017

    6. Article, “Create Claims with Confidence”, Natural Products Insider, June 2017

    7. Article, “New Research on Ingredients for Joint Pain”, Natural Products Insider, March 2017

    8. Quoted in “Kombucha Study Raises Sugar Content Questions”, BevNET, November 2016

    9. Article, “Beyond Non-GMO for Supplements”, Natural Products Insider, November 2016

    10. Article, “Two Identity Testing Requirements: References and Rigor”, Natural Products Insider, October 2016

    11. Article, “New Omega-3 Technologies Emerging”, Natural Products Insider, October 2016

    12. Article, “Probiotic Questions from the Gut,” Natural Products Insider, May/June 2016

    13. Article, “GNC, FDA Aim Alignment of U.S. with Global Standards”, Natural Products Insider, March 2016

    14. Article, “Modernization of the Supplement Industry”, Natural Products Insider, January 2016

    15. Article, “Eight Steps to Developing Research Relationships”,  Natural Products Insider, December 2015

    16. Article, “Supplier Verification Key to New Rules,”  Natural Products Insider, December 2015

    17. Article, “Where the Cannabis Market is Going”, Natural Products Insider, October 2015

    18. Article,  “Dosing and Quality Obstacles to Cannabis Adoption”, Supplement Perspectives, October 2015

    19. Article, “Welcome to the Gut Jungle”, Natural Products Insider, August 2015

    20. Article, “How to Design a Clinical Study”, Supplement Perspectives, June 2015

    21. Article, “Best Way to My Heart? Through the Gut”, Natural Products Insider, June 2015

    22. Article, “Immunity and Inflammation: Inseparable”, Supplement Perspectives, June 2015

    23. Article, “Capsaicin and Cannabis: The Hot and Cool of Joint Care”, Supplement Perspectives, April 2015

    24. Article, “How to Create Natural Product IP”, Supplement Perspectives, March 19, 2015

    25. Article, “The Athlete’s Frenemy: Inflammation”, Supplement Perspectives, February 2015

    26. Article, “Extracts: More than a Cup of Tea”, Natural Products Insider, February 2015

    27. Article, “Certifications are Fine, But…”, Natural Products Insider, January 2015

    28. Article, “Supplement Trends of 2014 and the Future”, Natural Products Insider, December 2014

    29. Article, “Traceability: What’s the Point?” Natural Products Insider, November 2014

    30. Article, “R&D: The Key Disciplines”, Supplement Perspectives, November 2014

    31. Article, “Dose Delivery: Oil into Water”, Natural Products Insider, August 2014

    32. Article, “Advances in Brain Health Research”, Natural Products Insider, July 2014

    33. Article, “Next-Gen Blood Sugar Management”, Natural Products Insider, June 2014

    34. Article, “Emerging Carotenoid Research”, Natural Products Insider, April 2014

    35. Special Issue, “Beyond Lutein”, Natural Products Insider, April 2014

    36. Article, “Sci-Fi, QC and Botanicals”, Natural Products Insider, March 2014

    37. Article, “Dose Delivery, Old & New”, Natural Products Insider, March 2014

    38. Article, “Beyond the Test Tube: Superfruit Science”, Natural Products Insider, Feb 2014

    39. Article, “Joint Health: Alternative Now Mainstream”, Natural Products Insider, Feb 2014

    40. Article, “Advancement Depends on Going Back to Basics”, Natural Products Insider, Dec 2013

    41. Article, “Consume Your Political News Frequently--and Calmly”, Natural Products Insider, November 2013

    42. Article, “The Eyes Are the Window to Our Health”, Natural Products Insider, October 2013

    43. Article, “Weighting to Lose”, SupplySide Community, October 2012

    44. Article, “Eyes Wide Open: Eye Health Supplements”, Natural Products Insider, August 2013

    45. Article, “The Gut-Brain Axis”, Natural Products Insider, August 2013

    46. Article, “Five Great Apps for Supplement Science ”, Natural Products Insider, July 2013

    47. Article, “Scientific Validity Keys for Supplement GMPs”, Natural Products Insider, June 2013

    48. Article, “Ingredient Spotlight: Pomegranate”, Nutritional Outlook, May 2013

    49. Article, “Sports Supplements: OK for Kids?”, Natural Products Insider, May 2013

    50. Article, “Your Trade Show Physical and Mental Health Checklist”, Natural Products Insider, April 2013

    51. Article, “Tips for Hiring the Right Contract Ingredient Manufacturer”, Natural Products Insider, March 2013

    52. Article, “Politics, Religion and Organic Farming”, Natural Products Insider, February 2013

    53. Article, “The Eyes Are the Window to.. Our Health”, Natural Products Insider, January 2013

    54. Article, “Silver Linings in Omega-3 Research”, Natural Products Insider, December 2012

    55. Article, “Why Antioxidants Are Useful”, Natural Products Insider, November 2012

    56. Article, “Weighting to Lose”, Natural Products Insider, October 2012

    57. Article, “The Bugs Are Taking Over”, SupplySide Community, September 2012 

    58. Quoted in “Encouraging Natural Bone Health”, Natural Practitioner, July/August 2012

    59. Quoted in “Boosting the Brain”, Nutrition Industry Executive, July/August 2012

    60. Article, “The Research Says It All: Omegas Do a Body Good”, SupplySide Community, August 2012 

    61. Article, “Ensuring Purity for Prenatal Supplements,” SupplySide Community, July 2012

    62. Article, “Are You in the 59 Percent?”, SupplySide Community, May 2012

    63. Article, “The Omnivore’s Inflammatory Dilemma”, SupplySide Community, April 2012 

    64. Article, “New Frontiers in Digestive Health”, SupplySide Community, March 2012

    65. Article, “Ch-ch changes in Senior Supplements”, SupplySide Community, February 2012 

 

Philanthropy

Giving Back is part of who we are.

Here are our favorite non-profit organizations that address poverty, hunger relief, diversity, environmental sustainability and herbal education:

-- American Botanical Council

-- Jim Duke's Green Farmacy Garden

-- JPW3

-- Mennonite Central Committee (Hunger Relief)

-- PBS

-- Second Helpings

-- United Plant Savers

-- Vitamin Angels

-- Wheeler Mission 

 

Recent NaturPro Articles

Our Mission

Our Vision: Plan for the Next Thousand Years

For thousands of years, natural products were central to health as food and medicine. After a short dark age for all things natural in the 1900s, a new renaissance has arrived.  The use of natural and healthy ingredients for health foods, dietary supplements, nutraceuticals and other health care products has exploded.

Today's challenges and opportunities are great. With increasing regulatory enforcement, aging populations, rapid advances in science and technology, a bustling and competitive global marketplace -- and consumer demand for quality and transparency -- the natural products industry is presented with a unique situation.

We have to think about the next thousand years and beyond. The circle of life can be completed with food and medicine from the earth, while fossil fuels and synthetic chemistry will not be sustainable sources of food and medicines at some point in the future. Seeds, soil and farmers are the sustainable lifeblood of foods and medicines, for as long as we can imagine into the future.  The NaturPro vision is to make natural products again central to health and life, by applying world-class science and stringent quality standards.