NaturPro Scientific – Natural Products Consultants

NaturPro Scientific is a boutique natural products consulting firm. We offer scientific expertise and solutions along the lifespan of healthy products that are better for consumers and better for the planet.  

NaturPro Scientific was founded on the basis that the food and supplement industry faces a number of challenges -- and an even greater number of opportunities.  NaturPro has spent years helping to develop quality standards, conduct research trials, develop products, and support compliance programs for a broad spectrum of clients in the supplement and food industries.

Some of our clients include startups, Fortune-50, mass market, as well as companies large and small in retail, specialty and online channels.

Part of the NaturPro advantage includes access to our team of experts, including some of the top legal, scientific, marketing and business minds in natural products.

We look forward to helping you on your journey.

Blake Ebersole

President

NaturPro Scientific, LLC

blake@npscientific.com

BIO: Blake Ebersole, B.S., M.B.A., founder and President of NaturPro Scientific LLC, is an expert in the development and production of natural products supporting human health for foods, drugs and dietary supplements. Trained in chemistry, Blake has worked from seed to shelf on successful innovation strategies that add lasting value to healthy consumer products, ingredients and raw materials. Blake has been integral in the development of numerous science-based products and ingredients supporting human health, leading to several patents and more than 70 peer-reviewed publications. 

Blake has spearheaded a number of compliance and quality management programs based on FDA, HACCP, GMP, GLP, GACP and ISO standards that govern regulated natural products industries around the globe. Blake is a contributing writer to industry trade and educational publications, and participates on standards-setting committees such as ASTM International, AOAC International and the American Herbal Products Association. 

Curriculum Vitae

About NaturPro:

NaturPro Scientific, LLC, is a boutique natural products scientific consulting firm offering more than 30 years of experience and solutions supporting the development of innovative and functional products and ingredients that promote human health. NaturPro provides essential seed-to-shelf guidance covering innovation, research, production, supplier verification, quality assurance and regulatory compliance. NaturPro supports a range of startups, midsize and Fortune-50 corporations in the dietary supplement, food and beverage, and other regulated industries. 

Active Members of:
American Botanical Council
American Herbal Products Association
AOAC International
ASTM International, Cannabis Committee

International Society of Sports Nutrition

U.S. Hemp Roundtable, Technical Committee

Recent Scientific Publications:

1. Historical Food and Supplement Adulterant List, Ebersole B. 2017, Self-published. Source: http://naturproscientific.com/historical-food-and-supplement-adulterant-list/ 
2. Curcumin Has Mixed Effects on Oxidative Stress in Patients with Nonmetastatic Prostate Cancer following Radiation Therapy, Ebersole B.  HerbClips™, American Botanical Council, September 2017
3. Aromatherapy Using Lavender Oil or Linalyl Acetate Modestly Improves Pain Relief in Patients with Colorectal Cancer following Post-surgery Catheter Removal, Ebersole B.  HerbClips™, American Botanical Council, September 2017
4. Loquat Leaf Extract without Additional Exercise Does Not Increase Muscle Mass in Healthy Adults, Ebersole B. HerbClips™, American Botanical Council, August 2017
5. Meta-analysis Provides Update of Aromatherapy for Depression, Ebersole B.  HerbClips™, American Botanical Council, August 2017
6. Petitgrain Oil Aromatherapy Reduces Markers of Stress and Modestly Improves Performance in Simulated Workplace Environment, Ebersole B.  HerbClips™, American Botanical Council, August 2017
7. Bromelain Improves Facial Swelling following Oral Surgery, Ebersole B. HerbClips™, American Botanical Council, July 2017
8. Single Serving of Montmorency Tart Cherry Concentrate Improves Cerebral Blood Flow, but Not Cognitive Function, Ebersole B. HerbClips™, American Botanical Council, August 2017
9. Kale Reduces Postprandial Spikes of Plasma Glucose in Healthy Japanese Adults, Ebersole B.  HerbClips™, American Botanical Council, July 2017
10. A Two-week, Pilot Study on the Reduction of Irritable Bowel Syndrome Symptoms with Atrantíl®, Ebersole B.  HerbClips™, American Botanical Council, July 2017
11. Hibiscus Water Extract Demonstrates Significant Antioxidant Effects in Patients with Marfan Syndrome, Ebersole B.  HerbClips™, American Botanical Council, June 2017
12. Weight Reduction with Meratrim® Botanical Extract Combination in Overweight Humans—A Randomized, Controlled Trial, Ebersole B.  HerbClips™, American Botanical Council, June 2017
13. Standardized Cranberry Extract, Cranpac™, Reduces Bacterial Adhesion in Patients with Recurrent Urinary Tract Infection, Ebersole B.  HerbClips™, American Botanical Council, May 2017
14. Efficacy of a Fruit and Vegetable Powder Supplement for Menopausal Symptoms in Women, Ebersole B.  HerbClips™, American Botanical Council, May 2017
15. Efficacy of Coenzyme Q10 and Tea Tree Oil for Chronic Periodontitis, Ebersole B.  HerbClips™, American Botanical Council, May 2017
16. Standardized Ginger Extract May Reduce Adverse Events from Tuberculosis Drugs, Ebersole B.  HerbClips™, American Botanical Council, April 2017
17. Review of Contact Dermatitis Associated with Tea Tree Oil Exposure, Ebersole B.  HerbClips™, American Botanical Council, June 2017
18. Efficacy of a Diet Program on Body Weight in Overweight Americans: Open‐Label Human Study. Ebersole B. March 2017. Technical Report, self-published on client website.
19. Pilot Studies on the Efficacy of a Diet Program on Body Weight in Overweight and Obese South Africans, Ebersole B. March 2017. Technical Report, self-published on client website.
20. Analysis of Sugars in Kombucha Tea by High Performance Liquid Chromatography, Ebersole B. Technical Report, October 2016. DOI: 10.13140/RG.2.2.24141.23522
21. AOAC International First Action Official Method 2016.12, Determination of Ethanol in Kombucha. Ebersole B. 
22. Single laboratory validation of a GC-FID method for ethanol in kombucha, Ebersole B, Eckert M, Schmidt R, Chan M, Brown P.  2017 Journal of AOAC, doi: 10.5740/jaoacint.16-0404
23. AOAC Standard Method Performance Requirements 2016.001. Journal of AOAC, (2016) 99(4), 1120-1121
24. Bitter melon extract attenuating hepatic steatosis may be mediated by FGF21 and AMPK/Sirt1 signaling in mice. Yu Y, Zhang XH, Ebersole B, Ribnicky D, Wang ZQ. Scientific Reports (Nature). 2013 Nov 5;3:3142. doi: 10.1038/srep03142.
25. Optimization and validation of ursolic acid by HPLC in Ocimum sanctum. Shah J, Patel S, Ebersole B, Hingorani L.  Planta Medica 2012 DOI: 10.1055/s-0032-1321177
26. Acute human pharmacokinetics of a lipid-dissolved turmeric extract, Shah J, Patel S, Ebersole B, Hingorani L. Planta Medica 2012 DOI: 10.1055/s-0032-1320664
27. Sustained cognitive effects and safety of HPLC-standardized Bacopa monnieri extract: A randomized, placebo controlled clinical trial. Hingorani L, Patel S, Ebersole B. Planta Medica 2012; DOI: 10.1055/s-0032-1320681

Poster Presentations:

1. Safety, tolerability and nutrient status after consuming a total meal replacement beverage for 30 days: a randomized, controlled pilot study in healthy adults. Ebersole B. International Society for Sports Nutrition Annual Meeting, June 7, 2018.
2. Single Laboratory Validation of Ethanol in Kombucha by Gas Chromatography with Flame Ionization Detection. Ebersole, B. AOAC International Annual Meeting, September 2016.
3. Ethanol analysis of kombucha products with gas chromatography. Ebersole B, Institute of Food Technologists Annual Meeting, 2016. 
4. Acute human pharmacokinetics of a lipid-dissolved turmeric extract. Shah J, Patel S, Ebersole B, Hingorani L.  2012 International Congress on Natural Products Research, New York, NY. July 31, 2012. Planta Med 2012; 78 - PH5 DOI: 10.1055/s-0032-1320664
5. High-throughput screening program for commercial single-herb extracts. Hingorani L, Seeram NP, Ebersole B.  2012 International Congress on Natural Products Research, New York, NY. July 31, 2012. Planta Med 2012; 78 - PF85 DOI: 10.1055/s-0032-1320632
6. Optimization and validation of ursolic acid by HPLC in Ocimum sanctum. Hingorani L, Ebersole B, Patel S.  2012 International Congress on Natural Products Research, New York, NY. July 31, 2012. 
7. Orthogonal validation of analytical and quality systems for botanical products. Hingorani L, Patel S, Darji B, Ebersole B.  2012 International Congress on Natural Products Research, New York, NY. July 31, 2012. Planta Med 2012; 78 - PJ156 DOI: 10.1055/s-0032-1321316
8. Sustained cognitive effects and safety of HPLC-standardized Bacopa monnieri extract: a randomized, placebo-controlled trial. Hingorani L, Patel S, Ebersole B.  2012 International Congress on Natural Products Research, New York, NY. July 31, 2012. 
9. Bitter melon extract enhances insulin sensitivity by modulating FGF21 signaling in high-fat diet fed mice. Wang ZQ, Yu Y, Zhang XH,  Li H, Qin J, Ebersole B, Cefalu WT. 7^th International Conference for Functional Foods in the Prevention and Management of Metabolic Syndrome,  Southern Methodist University, Dallas, TX, USA, December 3-4, 2010. 

Oral Presentations:

1. “Current Issues for Food Analysis”, Department of Nutrition and Food Science, Texas A&M University, October 25, 2017
2. “An Overview of the Food and Supplement Regulatory Climate”, Department of Nutrition and Food Science, Texas A&M University, March 16, 2017
3. “Identity Testing and Method Validation for Botanicals”, Supplyside West, October 5, 2016.
4. “Emerging Regulatory and Labeling Issues for Dietary Supplements and Foods”, Department of Nutrition and Food Science, Texas A&M University, September 5, 2016.
5. “Natural Products Research for Neurodegenerative Diseases”, NIH/NINDS, Bethesda, MD, March 3, 2015.
6. “Longvida: The Brain Curcumin”. Vitafoods International Conference, Geneva, Switzerland, May 24, 2012.
7. “100% Ingredient Identity”. SupplySide Marketplace Good Manufacturing Practices Workshop, NY, NY, May 8, 2012.
8. “Nutraceuticals: An Overview”. Department of Nutrition and Food Science, Texas A&M University, April 6, 2012.
9. “Fortification of Polyphenols into Functional Foods”.  Prepared Foods R&D Applications Seminar, Chicago, IL, USA, August 3, 2011. 
10. “Science-based Curcumin”, 16^th International Food Ingredients and Additives (IFIA) Conference, Tokyo Japan, May 19, 2011.
11. “Bioavailability of Botanical Supplements: Challenges and Opportunities”.  Department of Nutrition and Food Science, Texas A&M University, March 31, 2011.
12. “Foods Designed for Health, Functional Foods, and Nutraceuticals”.  Department of Nutrition and Food Science, Texas A&M University, March 20, 2008.

Published Articles in Non-Academic Press:

1. Press Release, “Botanical Liaisons and NaturPro Scientific Complete Independent Authentication of Rhodiolife® Rhodiola rosea L. Ingredient”, October 2017
2. Article, “Emerging Heart Health Ingredients”, Natural Products Insider, August 2017
3. Article, “Making a Quilt from the Regulatory Patchwork,” Natural Products Insider, July 2017
4. Article, “Create Claims with Confidence”, Natural Products Insider, June 2017
5. Article, “New Research on Ingredients for Joint Pain”, Natural Products Insider, March 2017
6. Quoted in “Kombucha Study Raises Sugar Content Questions”, BevNET, November 2016
7. Article, “Beyond Non-GMO for Supplements”, Natural Products Insider, November 2016
8. Article, “Two Identity Testing Requirements: References and Rigor”, Natural Products Insider, October 2016
9. Article, “New Omega-3 Technologies Emerging”, Natural Products Insider, October 2016
10. Article, “Probiotic Questions from the Gut,” Natural Products Insider, May/June 2016
11. Article, “GNC, FDA Aim Alignment of U.S. with Global Standards”, Natural Products Insider, March 2016
12. Article, “Modernization of the Supplement Industry”, Natural Products Insider, January 2016
13. Article, “Eight Steps to Developing Research Relationships”,  Natural Products Insider, December 2015
14. Article, “Supplier Verification Key to New Rules,”  Natural Products Insider, December 2015
15. Article, “Where the Cannabis Market is Going”, Natural Products Insider, October 2015
16. Article,  “Dosing and Quality Obstacles to Cannabis Adoption”, Supplement Perspectives, October 2015
17. Article, “Welcome to the Gut Jungle”, Natural Products Insider, August 2015
18. Article, “How to Design a Clinical Study”, Supplement Perspectives, June 2015
19. Article, “Best Way to My Heart? Through the Gut”, Natural Products Insider, June 2015
20. Article, “Immunity and Inflammation: Inseparable”, Supplement Perspectives, June 2015
21. Article, “Capsaicin and Cannabis: The Hot and Cool of Joint Care”, Supplement Perspectives, April 2015
22. Article, “How to Create Natural Product IP”, Supplement Perspectives, March 19, 2015
23. Article, “The Athlete’s Frenemy: Inflammation”, Supplement Perspectives, February 2015
24. Article, “Extracts: More than a Cup of Tea”, Natural Products Insider, February 2015
25. Article, “Certifications are Fine, But…”, Natural Products Insider, January 2015
26. Article, “Supplement Trends of 2014 and the Future”, Natural Products Insider, December 2014
27. Article, “Traceability: What’s the Point?” Natural Products Insider, November 2014
28. Article, “R&D: The Key Disciplines”, Supplement Perspectives, November 2014
29. Article, “Dose Delivery: Oil into Water”, Natural Products Insider, August 2014
30. Article, “Advances in Brain Health Research”, Natural Products Insider, July 2014
31. Article, “Next-Gen Blood Sugar Management”, Natural Products Insider, June 2014
32. Article, “Emerging Carotenoid Research”, Natural Products Insider, April 2014
33. Special Issue, “Beyond Lutein”, Natural Products Insider, April 2014
34. Article, “Sci-Fi, QC and Botanicals”, Natural Products Insider, March 2014
35. Article, “Dose Delivery, Old & New”, Natural Products Insider, March 2014
36. Article, “Beyond the Test Tube: Superfruit Science”, Natural Products Insider, Feb 2014
37. Article, “Joint Health: Alternative Now Mainstream”, Natural Products Insider, Feb 2014
38. Article, “Advancement Depends on Going Back to Basics”, Natural Products Insider, Dec 2013
39. Article, “Consume Your Political News Frequently--and Calmly”, Natural Products Insider, November 2013
40. Article, “The Eyes Are the Window to Our Health”, Natural Products Insider, October 2013
41. Article, “Weighting to Lose”, SupplySide Community, October 2012
42. Article, “Eyes Wide Open: Eye Health Supplements”, Natural Products Insider, August 2013
43. Article, “The Gut-Brain Axis”, Natural Products Insider, August 2013
44. Article, “Five Great Apps for Supplement Science ”, Natural Products Insider, July 2013
45. Article, “Scientific Validity Keys for Supplement GMPs”, Natural Products Insider, June 2013
46. Article, “Ingredient Spotlight: Pomegranate”, Nutritional Outlook, May 2013
47. Article, “Sports Supplements: OK for Kids?”, Natural Products Insider, May 2013
48. Article, “Your Trade Show Physical and Mental Health Checklist”, Natural Products Insider, April 2013
49. Article, “Tips for Hiring the Right Contract Ingredient Manufacturer”, Natural Products Insider, March 2013
50. Article, “Politics, Religion and Organic Farming”, Natural Products Insider, February 2013
51. Article, “The Eyes Are the Window to.. Our Health”, Natural Products Insider, January 2013
52. Article, “Silver Linings in Omega-3 Research”, Natural Products Insider, December 2012
53. Article, “Why Antioxidants Are Useful”, Natural Products Insider, November 2012
54. Article, “Weighting to Lose”, Natural Products Insider, October 2012
55. Article, “The Bugs Are Taking Over”, SupplySide Community, September 2012 
56. Quoted in “Encouraging Natural Bone Health”, Natural Practitioner, July/August 2012
57. Quoted in “Boosting the Brain”, Nutrition Industry Executive, July/August 2012
58. Article, “The Research Says It All: Omegas Do a Body Good”, SupplySide Community, August 2012 
59. Article, “Ensuring Purity for Prenatal Supplements,” SupplySide Community, July 2012
60. Article, “Are You in the 59 Percent?”, SupplySide Community, May 2012
61. Article, “The Omnivore’s Inflammatory Dilemma”, SupplySide Community, April 2012 
62. Article, “New Frontiers in Digestive Health”, SupplySide Community, March 2012
63. Article, “Ch-ch changes in Senior Supplements”, SupplySide Community, February 2012 

Giving Back is part of who we are.

Here are our favorite non-profit organizations that address poverty, hunger relief, diversity, environmental sustainability and herbal education:

American Botanical Council

Jim Duke's Green Farmacy Garden

JPW3

Mennonite Central Committee

PBS

Second Helpings

United Plant Savers

Vitamin Angels
Wheeler Mission